beta2-adrenergic receptor desensitization, internalization, and phosphorylation in response to full and partial agonists.
about
Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cellsDosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCRLigand internalization and recycling by human recombinant somatostatin type 4 (h sst(4)) receptors expressed in CHO-K1 cellsQuantitative modeling of GRK-mediated beta2AR regulationSodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal controlDiscovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor.G-protein coupled receptor kinases as modulators of G-protein signalling.Ligand-directed signalling at beta-adrenoceptorsTyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor.Discovery of regulators of receptor internalization with high-throughput flow cytometry.Beta-agonist intrinsic efficacy: measurement and clinical significance.Desensitization of beta2-adrenoceptor-mediated responses by short-acting beta2-adrenoceptor agonists in human lung mast cells.Desensitisation of mast cell beta2-adrenoceptor-mediated responses by salmeterol and formoterol.Influence of agonist intrinsic activity on the desensitisation of beta2-adrenoceptor-mediated responses in mast cells.Mutating the dileucine motif of the human beta(2)-adrenoceptor reduces the high initial rate of receptor phosphorylation by GRK without affecting postendocytic sorting.Salmeterol Efficacy and Bias in the Activation and Kinase-Mediated Desensitization of β2-Adrenergic Receptors.Long-acting beta2-agonists: comparative pharmacology and clinical outcomes.Relative myotoxic and haemodynamic effects of the beta-agonists fenoterol and clenbuterol measured in conscious unrestrained rats.Dose-dependent apoptotic and necrotic myocyte death induced by the beta2-adrenergic receptor agonist, clenbuterolPharmacogenomics of long-acting β2-agonists.Modelling the cardiovascular effects of ephedrineRibosomal S6 kinase 2 directly phosphorylates the 5-hydroxytryptamine 2A (5-HT2A) serotonin receptor, thereby modulating 5-HT2A signaling.The long-acting beta-adrenoceptor agonist, indacaterol, inhibits IgE-dependent responses of human lung mast cells.Agonist efficacy and receptor desensitization: from partial truths to a fuller picture.cAMP regulation of airway smooth muscle function.Efficacy and ligand bias at the μ-opioid receptor.Barcoding of GPCR trafficking and signaling through the various trafficking roadmaps by compartmentalized signaling networks.Endogenous Gs-coupled receptors in smooth muscle exhibit differential susceptibility to GRK2/3-mediated desensitizationAgonist-specific patterns of beta 2-adrenoceptor responses in human airway cells during prolonged exposure.A study of antagonist affinities for the human histamine H2 receptor.Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 function.Kinetic analysis of M2 muscarinic receptor activation of Gi in Sf9 insect cell membranes.beta-adrenergic agonists exert their "anti-inflammatory" effects in monocytic cells through the IkappaB/NF-kappaB pathway.The absence of a direct correlation between the loss of [D-Ala2, MePhe4,Gly5-ol]Enkephalin inhibition of adenylyl cyclase activity and agonist-induced mu-opioid receptor phosphorylation.Desensitization of beta2-adrenergic receptors with mutations of the proposed G protein-coupled receptor kinase phosphorylation sites.S-Palmitoylation of a Novel Site in the β2-Adrenergic Receptor Associated with a Novel Intracellular ItineraryFunctional desensitization of the β 2 adrenoceptor is not dependent on agonist efficacy.A composite computational model of liver glucose homeostasis. I. Building the composite model.Control of signalling efficacy by palmitoylation of the rat Y1 receptor.Salmeterol stimulation dissociates beta2-adrenergic receptor phosphorylation and internalization.
P2860
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P2860
beta2-adrenergic receptor desensitization, internalization, and phosphorylation in response to full and partial agonists.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
beta2-adrenergic receptor dese ...... to full and partial agonists.
@en
type
label
beta2-adrenergic receptor dese ...... to full and partial agonists.
@en
prefLabel
beta2-adrenergic receptor dese ...... to full and partial agonists.
@en
P2093
P2860
P356
P1476
beta2-adrenergic receptor dese ...... to full and partial agonists.
@en
P2093
Schonbrunn A
P2860
P304
23871-23879
P356
10.1074/JBC.272.38.23871
P407
P577
1997-09-01T00:00:00Z