Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells.

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ERAP1 and PDE8A Are Downregulated in Cattle Protected against Bovine Tuberculosis.Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)

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P2860

Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells.

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2017 nî lūn-bûn

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Synergistic inhibition effect ...... human multiple myeloma cells.

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Synergistic inhibition effect ...... human multiple myeloma cells.

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Synergistic inhibition effect ...... human multiple myeloma cells.

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Synergistic inhibition effect ...... human multiple myeloma cells.

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P2093

Jiyeon Kim

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Jung-Il Jung

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Kyeong-Yong Park

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Soon Ae Kim

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Yura Lee

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P2860

TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton

The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton

The kinase TNIK is an essential activator of Wnt target genes

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

Multiple myeloma

Apoptosis, oncosis, and necrosis. An overview of cell death

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Wnt signaling in B-cell neoplasia

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

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41091-41101

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scholarly article

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10.18632/ONCOTARGET.17056

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English

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2017-04-12T00:00:00Z

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5522218

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Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells.

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P2860

P2860

Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells.

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