The kinase TNIK is an essential activator of Wnt target genes
about
Smad inhibition by the Ste20 kinase MisshapenTCF/LEF Transcription Factors: An Update from the Internet ResourcesThe many faces and functions of β-cateninCell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentialsAgonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signallingNuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiationDISC1 at 10: connecting psychiatric genetics and neuroscienceThe leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasisThe inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cellsMINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor functionIdentification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathwaysInduction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein KinaseEmergence of TNIK inhibitors in cancer therapeutics.Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation.Whole genome expression profiling shows that BRG1 transcriptionally regulates UV inducible genes and other novel targets in human cellsMicroRNA roles in beta-catenin pathway.Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis.The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor.Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strainsAcetylation of human TCF4 (TCF7L2) proteins attenuates inhibition by the HBP1 repressor and induces a conformational change in the TCF4::DNA complex.The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.A novel aminothiazole KY-05009 with potential to inhibit Traf2- and Nck-interacting kinase (TNIK) attenuates TGF-β1-mediated epithelial-to-mesenchymal transition in human lung adenocarcinoma A549 cellsCan we safely target the WNT pathway?CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progressionPrognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer.Screening of reproduction-related single-nucleotide variations from MeDIP-seq data in sheep.Targeting Wnt pathways in disease.Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.TNIK inhibition abrogates colorectal cancer stemnessGene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer.TNiK is required for postsynaptic and nuclear signaling pathways and cognitive functionThe myc 3' wnt-responsive element suppresses colonic tumorigenesis.Drug discovery approaches to target Wnt signaling in cancer stem cells.How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway.The proteomics of cancer stem cells: potential clinical applications for innovative research in oncology.DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders.TCF/LEFs and Wnt signaling in the nucleus.Regulation of Wnt/β-catenin signaling by posttranslational modificationsTNIK serves as a novel biomarker associated with poor prognosis in patients with pancreatic cancer.Targeting the Wnt signaling pathway in colorectal cancer.
P2860
Q24307319-CFC8FB90-59A7-4C38-B22C-0EEBB475EEB8Q26742019-1038616A-5715-43A2-826F-F549B1A78132Q26865781-F00873E2-3787-4E13-9104-AC52781CD2C4Q27022532-E88AB561-8B60-4D50-84F4-29E7488DFF8EQ27323158-AEBC25AB-BD8D-4538-9A71-CC3E97D993B5Q28116474-3FF053E0-4627-4B9C-A95F-50F542755929Q28250914-23DEF498-0BB1-449B-9EC7-FB9D286E965CQ28476157-2AC24286-C2AD-4891-8AC5-B5A697E6A58DQ28487781-57FC78F3-9C97-42B5-A986-0923173C4517Q28578746-369F25CE-DB3E-4EEA-8B45-5C1503088448Q28591962-E5FB2E9C-7EC7-40F2-97E9-988EC4F233E1Q30386219-3F849BBE-6389-449E-AB2E-BA0EE43BB3D6Q33738834-D94A61B1-5310-4738-AB54-4EF580E68D95Q34074375-57899E06-59A4-423B-9D4B-3AA83C4B2348Q34089949-63E479E9-7071-4818-99C3-30D61F325786Q34202840-A84DAE44-6A96-4D19-95E4-3052010991C6Q34292029-DFA015D0-1618-4A66-B1CB-759EF6CA4500Q34384112-8B911C77-66F8-4300-A9F0-C335E8D414DEQ34413899-33B710A8-EC85-430F-9C3F-FBBC62D586BDQ34685322-454852A8-5146-49EF-83B6-4C51BACDA298Q35223834-00F61921-1A65-464F-A535-CBA66344F18BQ35357838-BE363B5D-140F-4228-B8A6-25D2521E1FA9Q35591995-E99B5D73-03A1-4FFE-AFE1-52B7E240F14AQ35698863-A5ED694F-B9A7-4115-8AC6-83C08AED9AC4Q35820715-33723719-6CCA-4012-BE05-830BD304CDCAQ36132584-A760C31D-35DC-4199-A14F-2CC0C60A9916Q36506697-76758665-241D-47AB-A12A-3EEC06275252Q36786350-B137DEBA-907A-49D3-8F11-C07EE9C9A974Q37223261-76F59BB3-0C87-41E9-9E68-92402E79E9EDQ37381860-0B2095A9-AB5D-4BC2-993C-5448B5F8011BQ37690413-D10CE7D0-04CF-4C93-A75C-19DC059FC807Q37713641-2F960E71-D77A-47B6-8BA2-88A21173FD6FQ37840943-CC2B5DFC-FA32-4439-9A43-F5E7E47CA0C4Q37882048-C513C238-D8A7-494D-8951-291EFDEF0292Q37940376-E18C233F-F226-4761-BEEA-93068D4B874AQ37998459-D3BE50C1-2A2C-4F8F-976E-82676D9C347FQ38048246-95E83329-6FAC-4A2F-9EEE-B20B68CADB1FQ38193259-E6011916-D29E-4359-9EDA-5797DC348D4DQ38384937-F295D958-1B8B-4F7A-A43D-C62D6EB773DFQ38600094-C92B529C-EE0C-48A5-A54E-E7E7EBBD7EAA
P2860
The kinase TNIK is an essential activator of Wnt target genes
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The kinase TNIK is an essential activator of Wnt target genes
@ast
The kinase TNIK is an essential activator of Wnt target genes
@en
The kinase TNIK is an essential activator of Wnt target genes
@en-gb
The kinase TNIK is an essential activator of Wnt target genes
@nl
type
label
The kinase TNIK is an essential activator of Wnt target genes
@ast
The kinase TNIK is an essential activator of Wnt target genes
@en
The kinase TNIK is an essential activator of Wnt target genes
@en-gb
The kinase TNIK is an essential activator of Wnt target genes
@nl
prefLabel
The kinase TNIK is an essential activator of Wnt target genes
@ast
The kinase TNIK is an essential activator of Wnt target genes
@en
The kinase TNIK is an essential activator of Wnt target genes
@en-gb
The kinase TNIK is an essential activator of Wnt target genes
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The kinase TNIK is an essential activator of Wnt target genes
@en
P2093
Nadia Taouatas
Robert G J Vries
Ser Sue Ng
Tokameh Mahmoudi
Vivian S W Li
P2860
P304
P3181
P356
10.1038/EMBOJ.2009.285
P407
P577
2009-11-04T00:00:00Z