Different effects of homo- and heterodimers of platelet-derived growth factor A and B chains on human and mouse fibroblasts.
about
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunitFunctions of the major tyrosine phosphorylation site of the PDGF receptor beta subunitIndependent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathwaysGastrointestinal stromal tumor and its targeted therapeutics.Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis.Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinasePDGF ligand and receptor gene expression during repair of arterial injury.Decreased level of PDGF-stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matrices.The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectivelyCa(2+)-channel blockers modulate expression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and low density lipoprotein receptor genes stimulated by platelet-derived growth factorActivation of Src family members is not required for the platelet-derived growth factor beta receptor to initiate mitogenesis.Induction of NF-kappa B-like activity by platelet-derived growth factor in mouse fibroblasts.Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and -independent mechanisms.PDGF A chain homodimers drive proliferation of bipotential (O-2A) glial progenitor cells in the developing rat optic nerve.Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cellsThe A-type receptor for platelet-derived growth factor mediates protein tyrosine phosphorylation, receptor transmodulation and a mitogenic response.
P2860
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P2860
Different effects of homo- and heterodimers of platelet-derived growth factor A and B chains on human and mouse fibroblasts.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Different effects of homo- and ...... n human and mouse fibroblasts.
@en
type
label
Different effects of homo- and ...... n human and mouse fibroblasts.
@en
prefLabel
Different effects of homo- and ...... n human and mouse fibroblasts.
@en
P2093
P2860
P1433
P1476
Different effects of homo- and ...... n human and mouse fibroblasts.
@en
P2093
A Kazlauskas
D Bowen-Pope
J A Cooper
P2860
P304
P407
P577
1988-12-01T00:00:00Z