Looking for protein stabilizing drugs with thermal shift assay. - Wikidata - wikimedia - TriplyDB

Looking for protein stabilizing drugs with thermal shift assay.

Looking for protein stabilizing drugs with thermal shift assay.

http://www.wikidata.org/entity/Q41112024

about

Identification of an Allosteric Binding Site on Human Lysosomal Alpha-Galactosidase Opens the Way to New Pharmacological Chaperones for Fabry Disease Heterodimerization of Two Pathological Mutants Enhances the Activity of Human Phosphomannomutase2 Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase).The Large Phenotypic Spectrum of Fabry Disease Requires Graduated Diagnosis and Personalized Therapy: A Meta-Analysis Can Help to Differentiate Missense Mutations Recent advances and novel treatments for sphingolipidoses.Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases.A mutant of phosphomannomutase1 retains full enzymatic activity, but is not activated by IMP: Possible implications for the disease PMM2-CDG.Structure and characterization of a class 3B proline utilization A: Ligand-induced dimerization and importance of the C-terminal domain for catalysis.The Analysis of Variants in the General Population Reveals That Is Extremely Tolerant to Missense Mutations and That Diagnosis of PMM2-CDG Can Benefit from the Identification of Modifiers

P2860

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P2860

Looking for protein stabilizing drugs with thermal shift assay.

http://www.wikidata.org/entity/Q41112024

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Looking for protein stabilizing drugs with thermal shift assay.

@en

type

label

Looking for protein stabilizing drugs with thermal shift assay.

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prefLabel

Looking for protein stabilizing drugs with thermal shift assay.

@en

P1433

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P2860

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Drug Testing and Analysis

P1476

Looking for protein stabilizing drugs with thermal shift assay

@en

P2093

Giuseppina Andreotti

http://www.w3.org/2001/XMLSchema#string

Maria Monticelli

http://www.w3.org/2001/XMLSchema#string

Maria Vittoria Cubellis

http://www.w3.org/2001/XMLSchema#string

P2860

Effects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and Stability

The Molecular Basis of Pharmacological Chaperoning in Human α-Galactosidase

Thermofluor-based high-throughput stability optimization of proteins for structural studies

High-density miniaturized thermal shift assays as a general strategy for drug discovery

Loss of protein structure stability as a major causative factor in monogenic disease.

Conformational response to ligand binding in phosphomannomutase2: insights into inborn glycosylation disorder.

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery.

Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.

Thermodynamic stability of carbonic anhydrase: measurements of binding affinity and stoichiometry using ThermoFluor.

A chaperone enhances blood α-glucosidase activity in Pompe disease patients treated with enzyme replacement therapy.

P304

831-834

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P31

scholarly article

P356

10.1002/DTA.1798

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P433

9

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P478

7

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P50

Maria Vittoria Cubellis

Giuseppina Andreotti

Maria Monticelli

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2015-04-05T00:00:00Z

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25845367

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6681132

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