Effects of epitope modification on T cell receptor-ligand binding and antigen recognition by seven H-2Kd-restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative.
about
T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APCT cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-lifeModulation of CD4 T cell function by soluble MHC II-peptide chimeras.A role for CD8 in the developmental tuning of antigen recognition and CD3 conformational change.Selective deletion of antigen-specific CD8+ T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporinA constant affinity threshold for T cell tolerance.Analysis, Isolation, and Activation of Antigen-Specific CD4(+) and CD8(+) T Cells by Soluble MHC-Peptide Complexes.Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy.Duality of the murine CD8 compartment.Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse.CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers.T cell recognition of hapten. Anatomy of T cell receptor binding of a H-2kd-associated photoreactive peptide derivative.Role of CD8 in aberrant function of cytotoxic T lymphocytes.Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex.The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge.Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignanciesThe Problem of Antigen Affinity Discrimination in B-Cell ImmunologyOriginal antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes
P2860
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P2860
Effects of epitope modification on T cell receptor-ligand binding and antigen recognition by seven H-2Kd-restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Effects of epitope modificatio ...... toreactive peptide derivative.
@en
type
label
Effects of epitope modificatio ...... toreactive peptide derivative.
@en
prefLabel
Effects of epitope modificatio ...... toreactive peptide derivative.
@en
P2093
P2860
P356
P1476
Effects of epitope modificatio ...... toreactive peptide derivative.
@en
P2093
Bassanini P
Cerottini JC
Luescher IF
P2860
P304
P356
10.1084/JEM.185.4.629
P407
P577
1997-02-01T00:00:00Z