The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells.
about
Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosisMembrane estrogen receptor-alpha levels predict estrogen-induced ERK1/2 activation in MCF-7 cellsThe Mechanism of Diarrhetic Shellfish Poisoning Toxin Production in Prorocentrum spp.: Physiological and Molecular PerspectivesNaringin-sensitive phosphorylation of plectin, a cytoskeletal cross-linking protein, in isolated rat hepatocytesEstablishment of okadaic acid resistant cell clones using a cDNA expression library.Extracts of Actinobacillus actinomycetemcomitans induce apoptotic cell death in human osteoblastic MG63 cells.Clostridium difficile toxin A elicits Ca(2+)-independent cytotoxic effects in cultured normal rat intestinal crypt cells.Role of protein phosphatases and mitochondria in the neuroprotective effects of estrogens.Effects of serine/threonine protein phosphatases on ion channels in excitable membranes.Mechanism targeted discovery of antitumor marine natural products.Sacrolide A, a new antimicrobial and cytotoxic oxylipin macrolide from the edible cyanobacterium Aphanothece sacrum.Inactivation of Bcl-2 by phosphorylationUse of marine toxins in combination with cytotoxic drugs for induction of apoptosis in acute myelogenous leukaemia cells.Okadaic acid, an apoptogenic toxin for symbiotic/parasitic annelids in the demosponge Suberites domunculaDegradation and dephosphorylation of focal adhesion kinase during okadaic acid-induced apoptosis in human neuroblastoma cells.The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters.Programmed cell death: concept, mechanism and control.Tumor necrosis factor-alpha-induced apoptosis in hepatocytes in long-term cultureTumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models.8-Chloro-cAMP induces apoptotic cell death in a human mammary carcinoma cell (MCF-7) line.Sulforaphane prevents microcystin-LR-induced oxidative damage and apoptosis in BALB/c miceProtein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements.Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from Streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells.Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.Novel Ser/Thr protein phosphatases in cell death regulationMechanism of okadaic acid-induced neuronal death and the effect of estrogensCell Death Inducing Microbial Protein Phosphatase Inhibitors--Mechanisms of Action.Antiproliferative activity of aqueous leaf extract of Annona muricata L. on the prostate, BPH-1 cells, and some target genes.Knockdown of phosphotyrosyl phosphatase activator induces apoptosis via mitochondrial pathway and the attenuation by simultaneous tau hyperphosphorylation.Identification of dynamic changes in proteins associated with the cellular cytoskeleton after exposure to okadaic acid.Induction of p53-independent apoptosis by simian virus 40 small t antigen.Loss of splicing factor ASF/SF2 induces G2 cell cycle arrest and apoptosis, but inhibits internucleosomal DNA fragmentationReversible protein phosphorylation modulates nucleotide excision repair of damaged DNA by human cell extracts.The methyl ester of okadaic acid is more potent than okadaic acid in disrupting the actin cytoskeleton and metabolism of primary cultured hepatocytesFine mapping of 28S rRNA sites specifically cleaved in cells undergoing apoptosis.Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis.Hamster pancreatic beta cell lines with altered sensitivity towards apoptotic signalling by phosphatase inhibitors.Evaluation of the use of two human cell lines for okadaic acid and DTX-1 determination by cytotoxicity assays and damage characterization.Apoptosis overview emphasizing the role of oxidative stress, DNA damage and signal-transduction pathways.Caspase I-related protease inhibition retards the execution of okadaic acid- and camptothecin-induced apoptosis and PAI-2 cleavage, but not commitment to cell death in HL-60 cells.
P2860
Q24682548-1CCAD9AB-32A4-44B3-A5AB-7D8232AAF581Q24796725-651D7EC6-E0D7-430E-A751-7F59ECD0A6EBQ28066933-6D950FF0-FC68-4B89-AE42-F1F7ED68E202Q28567931-4B21954B-4E76-41FE-BD41-0362C9605FAFQ30996073-0E04E1E5-D5B1-419F-9A96-674862935262Q33177738-1F6DB2A7-FC30-4C90-B75E-3CE811EA9321Q33609034-6A04C928-6B68-4808-9A71-32F371AA16EDQ33715371-92733F10-582E-4E75-9D55-3F97CD3A7A99Q33807200-EEC81A67-3B33-4943-AC91-D8974710DE22Q34012630-DE6C147A-6DFD-4D3C-AD81-CCBF010184E3Q34082204-88B4CC71-93CF-4404-864B-DF96502036C6Q34340301-76A2F189-7263-4C16-AEE2-17D7FA599E86Q34534299-4E798191-109D-4831-A414-214066EEB38FQ34719124-2A9507C5-6096-44BC-B31A-AA8C9586A549Q34773385-1C2DEF25-917C-4F3C-BFE2-3EA526AEEC08Q34975398-D5EABD98-0100-4558-B6C0-9B19AD71A34FQ35462471-BC97291F-985B-4A6A-A669-14043558137AQ35774157-B7577A4C-6FCA-42E8-ABBA-C372068A7F33Q35795137-5F0FCF1F-602A-41B9-B8D0-54FAEB19457AQ36081387-8C9BA307-74A2-48A4-B00B-BEC11F43F389Q36624151-1B23C9B1-7FE2-4F0B-827E-15F284BC6A10Q36677724-48181A81-3AC5-468B-81A2-EF660B506557Q36806678-5884ACC3-8B7E-4D61-84D4-33F50D76F12BQ37058555-7A8FD73B-0F41-466F-996F-9137F8B412FAQ37256583-D28EFC76-5645-4B7A-8932-DAD2A62691F1Q37307470-40519E1B-360D-4EED-8B33-E1DA42407F33Q38617357-ABB366BD-A4C0-4156-89A1-8141262070F4Q38939060-B58D1C76-D104-4E62-8370-DE9C2E153C76Q38995676-3D5CACB8-73D1-4B75-80B8-F6D179184122Q39147381-1050013E-3318-4D26-A82A-A44F3E83F029Q39604079-25AAF81D-9EA5-4B73-A039-0874CC0A65E1Q39705452-B87C0880-8CE2-4047-9A2A-DF5D2F635907Q39715390-AE085CA1-88A9-4E18-B3F2-B326B36C70ECQ39762594-F69D7DEB-7DA2-4D5E-AF6E-AB26F0065E54Q40016008-DACB70EB-6ECD-42AB-9E0A-93C96106E470Q40768035-B2360459-4A5F-4692-B19B-77DDBB0817C9Q40899179-4D387FE0-E81A-499F-94DC-978B10F525F9Q40943343-A158AA1D-8C66-49CF-93B3-39CDE3616E37Q40953209-35E0795B-247B-4C5E-AEC0-F48D2D7653E2Q40960316-60221937-4DA5-42A3-B5F9-67BBC1B8DF64
P2860
The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
The protein phosphatase inhibi ...... apoptosis in mammalian cells.
@en
type
label
The protein phosphatase inhibi ...... apoptosis in mammalian cells.
@en
prefLabel
The protein phosphatase inhibi ...... apoptosis in mammalian cells.
@en
P2093
P1476
The protein phosphatase inhibi ...... apoptosis in mammalian cells.
@en
P2093
P304
P356
10.1016/0014-4827(91)90523-W
P407
P577
1991-07-01T00:00:00Z