Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions.
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Alterations of tumor suppressor gene p16INK4a in pancreatic ductal carcinoma.E2F-6, a member of the E2F family that can behave as a transcriptional repressorStructure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activityCrystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutationsCellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)CDKN2A exon-wise deletion status and novel somatic mutations in Indian glioma patients.Irradiation selects for p53-deficient hematopoietic progenitors.Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model.A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: a maximum-likelihood combined linkage and association analysis in twins and their sibs.Hypermutability in carcinogenesisChimeras of p14ARF and p16: functional hybrids with the ability to arrest growthThe INK4a/ARF locus and melanoma.Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.Methylation and mutation analysis of p16 gene in gastric cancer.Tumor suppressor genetics.The CDKN2A (p16) gene and human cancer.Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations.Alteration of p16 and p15 genes in human uterine tumoursHigh prevalence of p16 genetic alterations in head and neck tumoursDefinition of the role of chromosome 9p21 in sporadic melanoma through genetic analysis of primary tumours and their metastases. The Melanoma Cooperative Group.Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cellsGenetics of coronary artery disease: focus on genome-wide association studies.DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.Establishment of a novel Chinese metastatic melanoma cell line showing the new cytogenetic and biological properties.Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.Genomic alterations in spontaneous and carcinogen-induced murine melanoma cell lines.A melanoma-associated germline mutation in exon 1beta inactivates p14ARF.p16/CDKN2 alterations and pRb expression in oesophageal squamous carcinoma.Functional reassessment of P16 variants using a transfection-based assay.P16 UV mutations in human skin epithelial tumors.Cdkn2a encodes functional variation of p16INK4a but not p19ARF, which confers selection in mouse lung tumorigenesis.Overall survival in aggressive B-cell lymphomas is dependent on the accumulation of alterations in p53, p16, and p27.Sequence variation and chromosomal mapping of the murine Cdkn2a tumor suppressor gene.Expression of p15 and p15.5 products in neuroendocrine lung tumours: relationship with p15(INK4b) methylation status.Comparative structure and characterization of a CDKN2 gene in a Xiphophorus fish melanoma model.CDKN2A Variants in a Population-Based Sample of Queensland Families With MelanomaMutations in theINK4a/ARFMelanoma Susceptibility Locus Functionally Impair p14ARF
P2860
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P2860
Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Compilation of somatic mutatio ...... ibution of base substitutions.
@en
type
label
Compilation of somatic mutatio ...... ibution of base substitutions.
@en
prefLabel
Compilation of somatic mutatio ...... ibution of base substitutions.
@en
P2093
P2860
P1476
Compilation of somatic mutatio ...... ibution of base substitutions.
@en
P2093
Hayward NK
Pearson JV
Pollock PM
P2860
P356
10.1002/(SICI)1098-2264(199602)15:2<77::AID-GCC1>3.0.CO;2-0
P577
1996-02-01T00:00:00Z