Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.
about
The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytesSHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activationCo-clustering of Fcgamma and B cell receptors induces dephosphorylation of the Grb2-associated binder 1 docking proteinAn immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactionsA novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processingPolymorphism and domain variability of human killer cell inhibitory receptorsOverexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activityDok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signalingInhibition of the Jun N-terminal protein kinase pathway by SHIP-1, a lipid phosphatase that interacts with the adaptor molecule Dok-3A double-edged kinase Lyn: a positive and negative regulator for antigen receptor-mediated signalsDifferential effects of B cell receptor and B cell receptor-FcgammaRIIB1 engagement on docking of Csk to GTPase-activating protein (GAP)-associated p62Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndromeSustained activation of Lyn tyrosine kinase in vivo leads to autoimmunityCD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76Inhibition of the function of the FcgammaRIIB by a monoclonal antibody to thymic shared antigen-1, a Ly-6 family antigenGenetics ignite focus on microglial inflammation in Alzheimer's diseaseMast cell activation: a complex interplay of positive and negative signaling pathwaysCross-presentation of IgG-containing immune complexesThe Role of FcRn in Antigen PresentationFcγ Receptors in Solid Organ TransplantationSoluble fibrinogen like protein 2 (sFGL2), the novel effector molecule for immunoregulationCD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium fluxp135 src homology 2 domain-containing inositol 5'-phosphatase (SHIPbeta ) isoform can substitute for p145 SHIP in fcgamma RIIB1-mediated inhibitory signaling in B cellsThe two SH2-domain-containing inositol 5-phosphatases SHIP1 and SHIP2 are coexpressed in human T lymphocytesThe Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cellsInterleukin-3 induces the association of the inositol 5-phosphatase SHIP with SHP2Inhibitory receptors abound?Tyrosine phosphorylation and relocation of SHIP are integrin-mediated in thrombin-stimulated human blood plateletsAssociation of tyrosine phosphatases SHP-1 and SHP-2, inositol 5-phosphatase SHIP with gp49B1, and chromosomal assignment of the geneInhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatasesSLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptorsInterleukin-4 alters early phagosome phenotype by modulating class I PI3K dependent lipid remodeling and protein recruitmentFCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signalingThe protein-tyrosine phosphatase SHP-2 associates with tyrosine-phosphorylated adhesion molecule PECAM-1 (CD31)Roles of C-terminal Src kinase in the initiation and the termination of the high affinity IgE receptor-mediated signalingTargeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life spanA dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- miceSHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKLThe src homology domain 2-containing inositol phosphatase SHIP forms a ternary complex with Shc and Grb2 in antigen receptor-stimulated B lymphocytes
P2860
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P2860
Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Role of the inositol phosphata ...... by the receptor Fc(gamma)RIIB.
@en
type
label
Role of the inositol phosphata ...... by the receptor Fc(gamma)RIIB.
@en
prefLabel
Role of the inositol phosphata ...... by the receptor Fc(gamma)RIIB.
@en
P2093
P356
P1433
P1476
Role of the inositol phosphata ...... by the receptor Fc(gamma)RIIB.
@en
P2093
P2888
P304
P356
10.1038/383263A0
P407
P577
1996-09-01T00:00:00Z
P6179
1048489084