Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance.
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Glucosamine for osteoarthritis: biological effects, clinical efficacy, and safety on glucose metabolismElevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosisHexosamines, insulin resistance, and the complications of diabetes: current status.Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauerEffects of oral glucosamine sulphate on serum glucose and insulin during an oral glucose tolerance test of subjects with osteoarthritisHyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylationDistinct effects of glucose and glucosamine on vascular endothelial and smooth muscle cells: evidence for a protective role for glucosamine in atherosclerosis.Hijacking the Hexosamine Biosynthetic Pathway to Promote EMT-Mediated Neoplastic PhenotypesO-GlcNAcylation and the Metabolic Shift in High-Proliferating Cells: All the Evidence Suggests that Sugars Dictate the Flux of Lipid Biogenesis in Tumor ProcessesInsulin receptor signaling in normal and insulin-resistant statesThe role of glucosamine-induced ER stress in diabetic atherogenesisFOXO transcription factors throughout T cell biologyFunctional O-GlcNAc modifications: implications in molecular regulation and pathophysiologyCancer cell metabolism: implications for therapeutic targetsGlycerol-3-phosphate acyltransferase-1 upregulation by O-GlcNAcylation of Sp1 protects against hypoxia-induced mouse embryonic stem cell apoptosis via mTOR activationInhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 AdipocytesGlucose and glucosamine regulate growth factor gene expression in vascular smooth muscle cellsGlutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesisFunctional regulation of glutamine:fructose-6-phosphate aminotransferase 1 (GFAT1) of Drosophila melanogaster in a UDP-N-acetylglucosamine and cAMP-dependent mannerCloning and partial characterization of the mouse glutamine:fructose-6-phosphate amidotransferase (GFAT) gene promoterA PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose.O-GlcNAc regulates FoxO activation in response to glucose.Quantification of O-GlcNAc protein modification in neutrophils by flow cytometry.Hexosamine pathway but not interstitial changes mediates glucotoxicity in pancreatic β-cells as assessed by cytosolic Ca2+ response to glucose.Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistanceThe hexosamine signaling pathway: O-GlcNAc cycling in feast or famineInfluence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway fluxThe role of O-GlcNAc signaling in the pathogenesis of diabetic retinopathy.Quantitative secretome and glycome of primary human adipocytes during insulin resistance.Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity.Bitterness in sugar: O-GlcNAcylation aggravates pre-B acute lymphocytic leukemia through glycolysis via the PI3K/Akt/c-Myc pathway.MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect.O-GlcNAcylation/phosphorylation cycling at Ser10 controls both transcriptional activity and stability of delta-lactoferrin.O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41.O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway.X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body.Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytesO-GlcNAc cycling: emerging roles in development and epigenetics.O-GlcNAc signaling in the cardiovascular system.Increased O-GlcNAc levels correlate with decreased O-GlcNAcase levels in Alzheimer disease brain.
P2860
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P2860
Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Discovery of a metabolic pathw ...... duction of insulin resistance.
@en
type
label
Discovery of a metabolic pathw ...... duction of insulin resistance.
@en
prefLabel
Discovery of a metabolic pathw ...... duction of insulin resistance.
@en
P2093
P921
P1476
Discovery of a metabolic pathw ...... duction of insulin resistance.
@en
P2093
Marshall S
Traxinger RR
P304
P407
P577
1991-03-01T00:00:00Z