Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate.
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N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipasePhospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionCrystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo- -linolenic acidImpact of CFTR DeltaF508 mutation on prostaglandin E2 production and type IIA phospholipase A2 expression by pulmonary epithelial cellsEnzymatic properties of human cytosolic phospholipase A(2)gammaHuman neuropathy target esterase catalyzes hydrolysis of membrane lipidsThe transfer of VLDL-associated phospholipids to activated platelets depends upon cytosolic phospholipase A2 activityFcgamma RI-triggered generation of arachidonic acid and eicosanoids requires iPLA2 but not cPLA2 in human monocytic cellsA novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifsEpstein-Barr virus primes human polymorphonuclear leucocytes for the biosynthesis of leukotriene B4Assessing phospholipase A2 activity toward cardiolipin by mass spectrometryInhibition of calcium-independent phospholipase A2 activity in rat hippocampus impairs acquisition of short- and long-term memoryEndothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerolCytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death.Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.Role of cytosolic phospholipase A(2) in retinal neovascularization.Functional characterization of a phospholipase A(2) homolog from Rickettsia typhi.Piperine inhibits the activities of platelet cytosolic phospholipase A2 and thromboxane A2 synthase without affecting cyclooxygenase-1 activity: different mechanisms of action are involved in the inhibition of platelet aggregation and macrophage infReorganization of actin cytoskeleton by the phosphoinositide metabolite glycerophosphoinositol 4-phosphateRickettsia typhi possesses phospholipase A2 enzymes that are involved in infection of host cells.Urothelial cell platelet-activating factor production mediated by calcium-independent phospholipase A2γ.Induction of cyclo-oxygenase-2 expression by methyl arachidonyl fluorophosphonate in murine J774 macrophages: roles of protein kinase C, ERKs and p38 MAPKPhospholipase A2 mediates apolipoprotein-independent uptake of chylomicron remnant-like particles by human macrophages.Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out miceURB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cellsCoherent anti-Stokes Raman scattering imaging of myelin degradation reveals a calcium-dependent pathway in lyso-PtdCho-induced demyelination.Activation of group IVC phospholipase A(2) by polycyclic aromatic hydrocarbons induces apoptosis of human coronary artery endothelial cellsOleamide: a fatty acid amide signaling molecule in the cardiovascular system?Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells.Tryptase activates calcium-independent phospholipase A2 and releases PGE2 in airway epithelial cells.Hypoxia-mediated impaired erythrocyte Lands' Cycle is pathogenic for sickle cell disease.Mechanisms involved in oleamide-induced vasorelaxation in rat mesenteric resistance arteries.Calcium-independent phospholipases in the heart: mediators of cellular signaling, bioenergetics, and ischemia-induced electrophysiologic dysfunctionRole of Ca2+-independent phospholipase A2 in cell growth and signaling.Phospholipase A2, oxidative stress, and neurodegeneration in binge ethanol-treated organotypic slice cultures of developing rat brain.Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signalingLiberating Chiral Lipid Mediators, Inflammatory Enzymes, and LIPID MAPS from Biological Grease.New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2.
P2860
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P2860
Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Irreversible inhibition of Ca( ...... arachidonyl fluorophosphonate.
@en
type
label
Irreversible inhibition of Ca( ...... arachidonyl fluorophosphonate.
@en
prefLabel
Irreversible inhibition of Ca( ...... arachidonyl fluorophosphonate.
@en
P2093
P1476
Irreversible inhibition of Ca( ...... arachidonyl fluorophosphonate.
@en
P2093
P356
10.1016/0005-2760(96)00002-1
P577
1996-07-01T00:00:00Z