Loss of DNA mismatch repair in acquired resistance to cisplatin.
about
MutS homologue hMSH5: role in cisplatin-induced DNA damage responseKu86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response elementNo significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatinMSH2 is essential for the preservation of genome integrity and prevents homeologous recombination in the moss Physcomitrella patensInteraction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatinMethylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramificationsMicrosatellite instability in colorectal cancerOverexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugsIncreased sensitivity of p53-deficient cells to anticancer agents due to loss of Pms2MSH2 missense mutations alter cisplatin cytotoxicity and promote cisplatin-induced genome instabilityProtein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove AdductsSystems biology of cisplatin resistance: past, present and futureSolution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link † , ‡Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-LinksChemoresistance and targeted therapies in ovarian and endometrial cancersA review of the clinical relevance of mismatch-repair deficiency in ovarian cancerInter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair researchAntitumor Activity of a 5-Hydroxy-1H-Pyrrol-2-(5H)-One-Based Synthetic Small Molecule In Vitro and In VivoLow frequency of replication errors in primary nervous system tumours.Photodynamic therapy of DNA mismatch repair-deficient and -proficient tumour cells.Mismatch repair and treatment resistance in ovarian cancer.The role of mismatch repair in the prevention of base pair mutations in Saccharomyces cerevisiae.The mismatch repair system modulates curcumin sensitivity through induction of DNA strand breaks and activation of G2-M checkpoint.Mismatch repair proteins are activators of toxic responses to chromium-DNA damage.The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedsideCombination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions.Allelic imbalance at p53 and microsatellite instability are predictive markers for resistance to chemotherapy in gastric carcinomaAlterations in p53 predict response to preoperative high dose chemotherapy in patients with gastric cancerSilencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular ConsequencesGene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.Cellular responses to Cisplatin-induced DNA damage.Parameters of Reserpine Analogs That Induce MSH2/MSH6-Dependent Cytotoxic ResponseFeatures of ovarian cancer in Lynch syndrome (Review).Apoptosis-related mRNA expression profiles of ovarian cancer cell lines following cisplatin treatment.Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins.Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts.Mismatch repair status and outcomes after adjuvant therapy in patients with surgically staged endometrial cancer.hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis.
P2860
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P2860
Loss of DNA mismatch repair in acquired resistance to cisplatin.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Loss of DNA mismatch repair in acquired resistance to cisplatin.
@en
type
label
Loss of DNA mismatch repair in acquired resistance to cisplatin.
@en
prefLabel
Loss of DNA mismatch repair in acquired resistance to cisplatin.
@en
P2093
P1433
P1476
Loss of DNA mismatch repair in acquired resistance to cisplatin.
@en
P2093
B Kurdi-Haidar
C R Boland
R D Christen
P304
P407
P577
1996-07-01T00:00:00Z