Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP.

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Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides.

P2860

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P2860

Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP.

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http://www.wikidata.org/entity/Q41194286

description

1990 nî lūn-bûn

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1990年の論文

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1990年論文

@yue

1990年論文

@zh-hant

1990年論文

@zh-hk

1990年論文

@zh-mo

1990年論文

@zh-tw

1990年论文

@wuu

1990年论文

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1990年论文

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name

Mechanisms of 2'-deoxyguanosin ...... onucleotide reductase by dGTP.

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type

Item

label

Mechanisms of 2'-deoxyguanosin ...... onucleotide reductase by dGTP.

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prefLabel

Mechanisms of 2'-deoxyguanosin ...... onucleotide reductase by dGTP.

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P1476

Mechanisms of 2'-deoxyguanosin ...... onucleotide reductase by dGTP.

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P2093

D S Duan

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F Waldman

http://www.w3.org/2001/XMLSchema#string

K Pawlak

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T Hoshino

http://www.w3.org/2001/XMLSchema#string

T Nagashima

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W Sadee

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P2860

Deoxyadenosine triphosphate as a mediator of deoxyguanosine toxicity in cultured T lymphoblasts

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleoside kinase(s).

Possible metabolic basis for the different immunodeficient states associated with genetic deficiencies of adenosine deaminase and purine nucleoside phosphorylase

Purinogenic immunodeficiency diseases. Differential effects of deoxyadenosine and deoxyguanosine on DNA synthesis in human T lymphoblasts.

Deoxyguanosine triphosphate as a possible toxic metabolite in the immunodeficiency associated with purine nucleoside phosphorylase deficiency.

Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: genetic model for immunodeficiency disease.

Selective toxicity of purine deoxynucleosides for human lymphocyte growth and function.

Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine.

Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity.

Deoxyguanosine toxicity on lymphoid cells as a cause for immunosuppression in purine nucleoside phosphorylase deficiency.

P304

725-731

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P31

scholarly article

P356

10.1042/BJ2680725

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English

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P478

268

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1990-06-01T00:00:00Z

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21042133

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2114100

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P921

purine nucleoside phosphorylase deficiency

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1131500

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Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP.

about

P2860

P2860

Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P921

P932