Signaling via the insulin-like growth factor-I receptor: does it differ from insulin receptor signaling?
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Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesisExtreme-longevity mutations orchestrate silencing of multiple signaling pathwaysTargeting the insulin-like growth factor pathway in hepatocellular carcinomaCrystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase. Implication for inhibitor specificityInsulin-like growth factor 1 has multisystem effects on foetal and preterm infant developmentModeling the Insulin-Like Growth Factor System in Articular CartilageApplication of insulin-like growth factor-1 in the treatment of inner ear disordersDifferential growth factor regulation of aspartyl-(asparaginyl)-beta-hydroxylase family genes in SH-Sy5y human neuroblastoma cells.Insulin-like growth factor 2 and its enterocyte receptor are not required for adaptation in response to massive small bowel resection.Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression.Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationHighly specific role of the insulin receptor in breast cancer progression.Insulin and Insulin-like Growth Factor 1 (IGF-1) Modulate Cytoplasmic Glucose and Glycogen Levels but Not Glucose Transport across the Membrane in Astrocytes.Blocking ligand occupancy of the alphaVbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells.An insulin-like peptide regulates egg maturation and metabolism in the mosquito Aedes aegypti.Myotubes derived from human-induced pluripotent stem cells mirror in vivo insulin resistance.Mapping growth-factor-modulated Akt signaling dynamics.The role of IGF-I and its binding proteins in the development of type 2 diabetes and cardiovascular disease.Insulin growth factor 1 receptor/PI3K/AKT survival pathway in outer segment membranes of rod photoreceptors.Role of IGF-1 in glucose regulation and cardiovascular disease.Insulin-like growth factor-1 receptor-targeted therapy for non-small cell lung cancer: a mini reviewCardiac aging and insulin resistance: could insulin/insulin-like growth factor (IGF) signaling be used as a therapeutic target?Phosphoinositide 3-kinase signaling in the vertebrate retina.Building the Case for Insulin-Like Growth Factor Receptor-I Involvement in Thyroid-Associated Ophthalmopathy.Inhibition of autophosphorylation of epidermal growth factor receptor by small peptides in vitro.Prospective cohort study evaluating risk factors for the development of pasture-associated laminitis in the United Kingdom.TNF down-regulation of receptor tyrosine kinase-dependent mitogenic signal pathways as an important step in cytostasis induction and commitment to apoptosis of Kym-1 rhabdomyosarcoma cells.Increased activity of the vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor TI-VAMP/VAMP7 by tyrosine phosphorylation in the Longin domain.Characterization of insulin-like growth factor I (IGF-I) receptor mutants for their effects on IGF-I- and interleukin 4-mediated DNA synthesis of 32D cells.Cell-cycle-dependent turnover of P-glycoprotein in multidrug-resistant cells.Structure and function of the insulin-like growth factor I receptor.Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function.Possible involvement of IGF-1 receptor and IGF-binding protein in insulin-induced enhancement of noradrenaline response in diabetic rat aorta.Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNTIGF-I induced phosphorylation of S6K1 and 4E-BP1 in heart is impaired by acute alcohol intoxication.Regulation of insulin-like growth factor I receptor dephosphorylation by SHPS-1 and the tyrosine phosphatase SHP-2.Short-term insulin treatment and aortic expressions of IGF-1 receptor and VEGF mRNA in diabetic rats.IGF-I induces DNA synthesis and apoptosis in rat liver hepatic stellate cells (HSC) but DNA synthesis and proliferation in rat liver myofibroblasts (rMF).Epithelial IGF1R is dispensable for IGF2 mediated enhanced intestinal adaptation in retinoblastoma-deficient mice.
P2860
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P2860
Signaling via the insulin-like growth factor-I receptor: does it differ from insulin receptor signaling?
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Signaling via the insulin-like ...... om insulin receptor signaling?
@en
type
label
Signaling via the insulin-like ...... om insulin receptor signaling?
@en
prefLabel
Signaling via the insulin-like ...... om insulin receptor signaling?
@en
P2093
P1476
Signaling via the insulin-like ...... om insulin receptor signaling?
@en
P2093
Blakesley VA
Esposito D
Le Roith D
Scrimgeour A
P304
P356
10.1016/1359-6101(96)00015-9
P577
1996-08-01T00:00:00Z