Functional significance of the nuclear-targeting and NTP-binding motifs of Semliki Forest virus nonstructural protein nsP2.
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Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2Functional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activityAlphavirus RNA synthesis and non-structural protein functionsHelicase and capping enzyme active site mutations in brome mosaic virus protein 1a cause defects in template recruitment, negative-strand RNA synthesis, and viral RNA capping.Effects of palmitoylation of replicase protein nsP1 on alphavirus infectionThe carboxy-terminal acidic domain of Rift Valley Fever virus NSs protein is essential for the formation of filamentous structures but not for the nuclear localization of the protein.Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive MutantsCoordinate Replication of Alfalfa Mosaic Virus RNAs 1 and 2 Involves cis- and trans-Acting Functions of the Encoded Helicase-Like and Polymerase-Like DomainsRandom insertion mutagenesis of sindbis virus nonstructural protein 2 and selection of variants incapable of downregulating cellular transcriptionNTPase and 5' to 3' RNA duplex-unwinding activities of the hepatitis E virus helicase domain.RNA helicase activity of Semliki Forest virus replicase protein NSP2.A single amino acid change in the nuclear localization sequence of the nsP2 protein affects the neurovirulence of Semliki Forest virus.Comparison of two aquatic alphaviruses, salmon pancreas disease virus and sleeping disease virus, by using genome sequence analysis, monoclonal reactivity, and cross-infection.Different phenotypes in vivo are associated with ATPase motif mutations in Schizosaccharomyces pombe minichromosome maintenance proteinsRIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replicationSemliki forest virus-based expression for versatile use in receptor research.Semliki Forest virus nonstructural protein 2 is involved in suppression of the type I interferon response.Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein.ATM kinase is activated by sindbis viral vector infection.Role for conserved residues of sindbis virus nonstructural protein 2 methyltransferase-like domain in regulation of minus-strand synthesis and development of cytopathic infection.RNA chaperones encoded by RNA viruses.Hypervariable domain of nonstructural protein nsP3 of Venezuelan equine encephalitis virus determines cell-specific mode of virus replication.Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells.A new role for ns polyprotein cleavage in Sindbis virus replication.Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virusVenezuelan equine encephalitis virus capsid protein inhibits nuclear import in Mammalian but not in mosquito cellsPseudo-typed Semliki Forest virus delivers EGFP into neurons.Improved Semliki Forest virus vectors for receptor research and gene therapy.Venezuelan Equine Encephalitis Virus Capsid-The Clever Caper.Fate of minus-strand templates and replication complexes produced by a p23-cleavage-defective mutant of Sindbis virus.Nuclear import and export of Venezuelan equine encephalitis virus nonstructural protein 2.Site-specific protease activity of the carboxyl-terminal domain of Semliki Forest virus replicase protein nsP2.Characterization of the cysteine protease domain of Semliki Forest virus replicase protein nsP2 by in vitro mutagenesis.Identification of a Novel Function of theAlphavirusCapping Apparatus
P2860
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P2860
Functional significance of the nuclear-targeting and NTP-binding motifs of Semliki Forest virus nonstructural protein nsP2.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Functional significance of the ...... us nonstructural protein nsP2.
@en
type
label
Functional significance of the ...... us nonstructural protein nsP2.
@en
prefLabel
Functional significance of the ...... us nonstructural protein nsP2.
@en
P356
P1433
P1476
Functional significance of the ...... us nonstructural protein nsP2.
@en
P2093
Rikkonen M
P304
P356
10.1006/VIRO.1996.0204
P407
P577
1996-04-01T00:00:00Z