Efficient modification of human chromosomal alleles using recombination-proficient chicken/human microcell hybrids.
about
P1343
Formation of a large, complex domain of histone hyperacetylation at human 14q32.1 requires the serpin locus control regionDifferential regulation of gene activity and chromatin structure within the human serpin gene cluster at 14q32.1 in macrophage microcell hybrids.The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells.Stable expression and cell-specific chromatin structure of human alpha1-antitrypsin cosmid transgenes in rat hepatoma cells.Long-distance control of origin choice and replication timing in the human beta-globin locus are independent of the locus control region.Human matrix attachment regions insulate transgene expression from chromosomal position effects in Drosophila melanogaster.Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering.Genetic modification of mammalian genome at chromosome level.The chicken as a model for large-scale analysis of vertebrate gene function.Strategies for engineering human chromosomes with therapeutic potential.Rescue of targeted regions of mammalian chromosomes by in vivo recombination in yeastChromosomal elements regulate gene activity and chromatin structure of the human serpin gene cluster at 14q32.1.The HNF-4/HNF-1alpha transactivation cascade regulates gene activity and chromatin structure of the human serine protease inhibitor gene cluster at 14q32.1.The locus control region activates serpin gene expression through recruitment of liver-specific transcription factors and RNA polymerase II.The human beta-globin replication initiation region consists of two modular independent replicatorsAn insulator embedded in the chicken α-globin locus regulates chromatin domain configuration and differential gene expression.Efficient modification of a human chromosome by telomere-directed truncation in high homologous recombination-proficient chicken DT40 cells.GATA-1 modulates the chromatin structure and activity of the chicken alpha-globin 3' enhancer.Targeted deletion of the chicken beta-globin regulatory elements reveals a cooperative gene silencing activity.Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human beta-globin locusAntibody-targeted cell fusion.Functional evidence for a telomerase repressor gene on human chromosome 10p15.1.Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts.Transchromosomal mouse embryonic stem cell lines and chimeric mice that contain freely segregating segments of human chromosome 21.Contribution of zebrafish-mouse cell hybrids to the mapping of the zebrafish genome.Epigenetic reprogramming of the human H19 gene in mouse embryonic cells does not erase the primary parental imprint.Site-Specific Cleavage by Topoisomerase 2: A Mark of the Core Centromere.
P2860
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P2860
Efficient modification of human chromosomal alleles using recombination-proficient chicken/human microcell hybrids.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Efficient modification of huma ...... icken/human microcell hybrids.
@en
type
label
Efficient modification of huma ...... icken/human microcell hybrids.
@en
prefLabel
Efficient modification of huma ...... icken/human microcell hybrids.
@en
P2093
P2860
P356
P1433
P1476
Efficient modification of huma ...... hicken/human microcell hybrids
@en
P2093
P2860
P2888
P304
P356
10.1038/NG0296-174
P407
P4510
P577
1996-02-01T00:00:00Z
P6179
1017853247