Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts. - Wikidata - wikimedia - TriplyDB

Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts.

Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts.

http://www.wikidata.org/entity/Q40851453

about

Meiotic transmission of an in vitro-assembled autonomous maize minichromosome A new generation of human artificial chromosomes for functional genomics and gene therapy Refined human artificial chromosome vectors for gene therapy and animal transgenesis A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges Physiological level production of antigen-specific human immunoglobulin in cloned transchromosomic cattle Novel method to load multiple genes onto a mammalian artificial chromosome Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts Modeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organization A method for producing transgenic cells using a multi-integrase system on a human artificial chromosome vector Bi-HAC vector system toward gene and cell therapy Human artificial chromosome with a conditional centromere for gene delivery and gene expression.A novel system for simultaneous or sequential integration of multiple gene-loading vectors into a defined site of a human artificial chromosome Strategies for engineering human chromosomes with therapeutic potential.TransChromo Mouse.Hybridoma-free generation of monoclonal antibodies.Human artificial chromosomes for gene delivery and the development of animal models Species-Specific Chromosome Engineering Greatly Improves Fully Human Polyclonal Antibody Production Profile in Cattle.Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette.Development of mammalian artificial chromosomes for the treatment of genetic diseases: Sandhoff and Krabbe diseases.Human antibodies from transgenic animals.Genomically humanized mice: technologies and promises.Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function.Nucleic-acid based gene therapeutics: delivery challenges and modular design of nonviral gene carriers and expression cassettes to overcome intracellular barriers for sustained targeted expression.Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology.De novo formed satellite DNA-based mammalian artificial chromosomes and their possible applications.Functional complementation of a genetic deficiency with human artificial chromosomes.Engineering cell-based therapies to interface robustly with host physiology.Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.Cell to cell transfer of the chromatin-packaged human beta-globin gene cluster.Human artificial chromosomes constructed using the bottom-up strategy are stably maintained in mitosis and efficiently transmissible to progeny mice.Analysis of mitotic and expression properties of human neocentromere-based transchromosomes in mice.Manipulating transgenes using a chromosome vector Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies.CRISPR/Cas9-induced transgene insertion and telomere-associated truncation of a single human chromosome for chromosome engineering in CHO and A9 cells.Replication of somatic micronuclei in bovine enucleated oocytes.Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies

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P2860

Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts.

http://www.wikidata.org/entity/Q40851453

description

2000 nî lūn-bûn

@nan

2000年の論文

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2000年学术文章

@wuu

2000年学术文章

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2000年学术文章

@zh-hans

2000年学术文章

@zh-my

2000年学术文章

@zh-sg

2000年學術文章

@yue

2000年學術文章

@zh

2000年學術文章

@zh-hant

name

Manipulation of human minichro ...... base-sized chromosome inserts.

@en

type

label

Manipulation of human minichro ...... base-sized chromosome inserts.

@en

prefLabel

Manipulation of human minichro ...... base-sized chromosome inserts.

@en

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P1433

Nature Biotechnology

P1476

Manipulation of human minichro ...... base-sized chromosome inserts.

@en

P2093

Ishida I

http://www.w3.org/2001/XMLSchema#string

Kazuki Y

http://www.w3.org/2001/XMLSchema#string

Kuroiwa Y

http://www.w3.org/2001/XMLSchema#string

Ohguma A

http://www.w3.org/2001/XMLSchema#string

Oshimura M

http://www.w3.org/2001/XMLSchema#string

Shinohara T

http://www.w3.org/2001/XMLSchema#string

Tanaka S

http://www.w3.org/2001/XMLSchema#string

Tomizuka K

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Yamamoto T

http://www.w3.org/2001/XMLSchema#string

Yoshida H

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P2860

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector

The DNA sequence of human chromosome 22

Formation of de novo centromeres and construction of first-generation human artificial microchromosomes

Detection and characterization of chimeric yeast artificial-chromosome clones.

Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection.

Cre-mediated site-specific translocation between nonhomologous mouse chromosomes

Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors.

Recycling selectable markers in mouse embryonic stem cells.

Production of homozygous mutant ES cells with a single targeting construct.

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1086-1090

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scholarly article

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10.1038/80287

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10

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18

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2000-10-01T00:00:00Z

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12306791

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1010538586

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11017048

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