Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.
about
2-Aminoadipic acid is a biomarker for diabetes riskTesting pancreatic islet function at the single cell level by calcium influx with associated marker expressionHeterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass.Sodium-calcium exchanger 1 regulates epithelial cell migration via calcium-dependent extracellular signal-regulated kinase signaling.β-Cell preservation and regeneration in diabetes by modulation of β-cell Ca²⁺ homeostasis.Roles of ion transport in control of cell motility.Triton X-100 inhibits L-type voltage-operated calcium channels.Local and regional control of calcium dynamics in the pancreatic islet.Heterozygous inactivation of plasma membrane Ca(2+)-ATPase in mice increases glucose-induced insulin release and beta cell proliferation, mass and viability.Pretreatment of donor islets with the Na(+) /Ca(2+) exchanger inhibitor improves the efficiency of islet transplantation.Na+/Ca2+ Exchanger a Druggable Target to Promote β-Cell Proliferation and Function.
P2860
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P2860
Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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2010年學術文章
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2010年學術文章
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name
Inhibition of beta-cell sodium ...... calcium and insulin secretion.
@en
type
label
Inhibition of beta-cell sodium ...... calcium and insulin secretion.
@en
prefLabel
Inhibition of beta-cell sodium ...... calcium and insulin secretion.
@en
P2093
P2860
P356
P1433
P1476
Inhibition of beta-cell sodium ...... calcium and insulin secretion
@en
P2093
Daniel Soliman
David A Liknes
Gavin J Searle
Jason R B Dyck
Kevin S C Hamming
Laura C Matemisz
Michael J Riedel
Nicola J Webster
Peter E Light
Xiao-Qing Dai
P2860
P304
P356
10.2337/DB09-0630
P407
P577
2010-04-22T00:00:00Z