Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.
about
PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodiaNegative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1HsMSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblastsPhosphorylation of myosin light chain kinase by p21-activated kinase PAK2Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylationSPECs, small binding proteins for Cdc42Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyreneThe hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory functionRac1-induced cell migration requires membrane recruitment of the nuclear oncogene SETThe C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikisRegulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding.LOK is a novel mouse STE20-like protein kinase that is expressed predominantly in lymphocytesHPK1, a hematopoietic protein kinase activating the SAPK/JNK pathwayActivation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway.Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganizationCharacterization of the structure and function of a new mitogen-activated protein kinase (p38beta)Identification of a novel Rac1-interacting protein involved in membrane rufflingCharacterization of the structure and function of a novel MAP kinase kinase (MKK6)CDC42 and FGD1 cause distinct signaling and transforming activities.MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cellsMAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migrationTrophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinizationFRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophagesTranslocation of PKN from the cytosol to the nucleus induced by stressesRegulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organizationExpression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexesMKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathwayIQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilamentsHuman miR-221/222 in Physiological and Atherosclerotic Vascular RemodelingA RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cellsNovel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Kinase Signaling in Apoptosis Induced by Saturated Fatty Acids in Pancreatic β-CellsRin GTPase couples nerve growth factor signaling to p38 and b-Raf/ERK pathways to promote neuronal differentiationMultisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activationA tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins
P2860
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P2860
Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Rho family GTPases regulate p3 ...... the downstream mediator Pak1.
@en
type
label
Rho family GTPases regulate p3 ...... the downstream mediator Pak1.
@en
prefLabel
Rho family GTPases regulate p3 ...... the downstream mediator Pak1.
@en
P2093
P356
P1476
Rho family GTPases regulate p3 ...... the downstream mediator Pak1.
@en
P2093
Chernoff J
Ulevitch RJ
P304
23934-23936
P356
10.1074/JBC.270.41.23934
P407
P577
1995-10-01T00:00:00Z