Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice. - Wikidata - wikimedia - TriplyDB

Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice.

Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice.

http://www.wikidata.org/entity/Q41301488

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Vascular patterning sets the stage for macro and micro hepatic architecture Intestinal activation of Notch signaling induces rapid onset hepatic steatosis and insulin resistance Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi Micro-computed tomography and nuclear magnetic resonance imaging for noninvasive, live-mouse cholangiography.Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis Regulation of biliary proliferation by neuroendocrine factors: implications for the pathogenesis of cholestatic liver diseases.Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis.Functional and structural features of cholangiocytes in health and disease.Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.Crosstalk between Nrf2 and Notch signaling.3-dimensional resin casting and imaging of mouse portal vein or intrahepatic bile duct system.Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi)Robust cellular reprogramming occurs spontaneously during liver regeneration.Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling.Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice.Stages based molecular mechanisms for generating cholangiocytes from liver stem/progenitor cells.Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling.RNAi-nanoparticulate manipulation of gene expression as a new functional genomics tool in the liver.Liver stem/progenitor cells: their characteristics and regulatory mechanisms.Ductal plates in hepatic ductular reactions. Hypothesis and implications. III. Implications for liver pathology.Development of the bile ducts: essentials for the clinical hepatologist.Differentiation of progenitors in the liver: a matter of local choice Vascular biology of the biliary epithelium Emerging roles of Notch signaling in liver disease.Adaptive remodeling of the biliary tree: the essence of liver progenitor cell expansion.Relationship between hepatic progenitor cell-mediated liver regeneration and non-parenchymal cells.Current strategies to generate mature human induced pluripotent stem cells derived cholangiocytes and future applications.Inhibition of notch signaling pathway prevents cholestatic liver fibrosis by decreasing the differentiation of hepatic progenitor cells into cholangiocytes.The liver is a peculiar organ when it comes to stem cells Intrahepatic bile duct regeneration in mice does not require Hnf6 or Notch signaling through Rbpj Genetic interactions between hepatocyte nuclear factor-6 and Notch signaling regulate mouse intrahepatic bile duct development in vivo.Human hepatic organoids for the analysis of human genetic diseases.Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1.Notch Signaling in Development, Tissue Homeostasis, and Disease.Three-dimensional structural analysis reveals a Cdk5-mediated kinase cascade regulating hepatic biliary network branching in zebrafish.

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P2860

Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice.

http://www.wikidata.org/entity/Q41301488

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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2010年學術文章

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2010年學術文章

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Notch signaling regulates form ...... trahepatic bile ducts in mice.

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Notch signaling regulates form ...... trahepatic bile ducts in mice.

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Notch signaling regulates form ...... trahepatic bile ducts in mice.

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Notch signaling regulates form ...... ntrahepatic bile ducts in mice

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Kari A Huppert

http://www.w3.org/2001/XMLSchema#string

M Kay Washington

http://www.w3.org/2001/XMLSchema#string

Melanie A Brown

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Stacey S Huppert

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P2860

NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

Notch signaling controls multiple steps of pancreatic differentiation

Generalized lacZ expression with the ROSA26 Cre reporter strain

A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency

Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors

Notch1 is required for the coordinate segmentation of somites

gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis

Notch signaling is essential for vascular morphogenesis in mice

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10.1002/HEP.23431

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