A 22-mer segment in the structurally pliable regulatory domain of metazoan CTP: phosphocholine cytidylyltransferase facilitates both silencing and activating functions.
about
The biophysics and cell biology of lipid dropletsStructural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic HelixAlpha-synuclein function and dysfunction on cellular membranes.Molecular Mechanism for the Thermo-Sensitive Phenotype of CHO-MT58 Cell Line Harbouring a Mutant CTP:Phosphocholine CytidylyltransferaseMutations in PCYT1A, encoding a key regulator of phosphatidylcholine metabolism, cause spondylometaphyseal dysplasia with cone-rod dystrophy.Mechanistic insights into the nongenomic regulation of phospholipid synthesizing enzymes.Diacylglycerol Acyltransferase 1 Is Regulated by Its N-Terminal Domain in Response to Allosteric Effectors.Not an exception to the rule: the functional significance of intrinsically disordered protein regions in enzymes.An auto-inhibitory helix in CTP:phosphocholine cytidylyltransferase hi-jacks the catalytic residue and constrains a pliable, domain-bridging helix pair.Heterologous expression of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum rescues Chinese Hamster Ovary cells deficient in the Kennedy phosphatidylcholine biosynthesis pathway.Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesisMembrane-binding mechanism of a bacterial phospholipid N-methyltransferase
P2860
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P2860
A 22-mer segment in the structurally pliable regulatory domain of metazoan CTP: phosphocholine cytidylyltransferase facilitates both silencing and activating functions.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A 22-mer segment in the struct ...... cing and activating functions.
@en
type
label
A 22-mer segment in the struct ...... cing and activating functions.
@en
prefLabel
A 22-mer segment in the struct ...... cing and activating functions.
@en
P2093
P2860
P356
P1476
A 22-mer segment in the struct ...... cing and activating functions.
@en
P2093
Harris K H Huang
Lucie Semenec
Nansheng Chen
Rosemary B Cornell
Stephanie A Campbell
Svetla G Taneva
Ziwei Ding
P2860
P304
38980-38991
P356
10.1074/JBC.M112.402081
P407
P577
2012-09-17T00:00:00Z