Active site electrostatics protect genome integrity by blocking abortive hydrolysis during DNA recombination.
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Requirements for catalysis in the Cre recombinase active siteReactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomeraseElectrostatic suppression allows tyrosine site-specific recombination in the absence of a conserved catalytic arginineRestoration of catalytic functions in Cre recombinase mutants by electrostatic compensation between active site and DNA substrate.The partitioning and copy number control systems of the selfish yeast plasmid: an optimized molecular design for stable persistence in host cells.Stereospecific suppression of active site mutants by methylphosphonate substituted substrates reveals the stereochemical course of site-specific DNA recombination.Real-time single-molecule tethered particle motion analysis reveals mechanistic similarities and contrasts of Flp site-specific recombinase with Cre and λ IntHolliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase.The Borrelia burgdorferi telomere resolvase, ResT, possesses ATP-dependent DNA unwinding activity.
P2860
Q27661545-3113D2F9-0145-4480-8D4F-97B03A3F347FQ33507514-2A40D278-140D-4F81-9F1E-1E3C532800C2Q34003886-C981C71D-98CA-4F54-9926-7B651B1E5C84Q34246677-3E0DAAD2-BD69-4E1C-8F73-ED82A1EA5250Q34763487-B92F6873-C96E-4EBE-8621-FECFD6070C3BQ35842506-E9E7E5CD-E80F-441E-A652-DDA165CA18E5Q37080351-D02A2A5C-E0B0-492B-9BF5-6EFA546DF321Q37574376-B9EAA06C-73F1-4CD8-96A8-8122A219DD6CQ42254485-A0BF8B47-248F-420C-8A74-A3716AEF66D9
P2860
Active site electrostatics protect genome integrity by blocking abortive hydrolysis during DNA recombination.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Active site electrostatics pro ...... ysis during DNA recombination.
@en
type
label
Active site electrostatics pro ...... ysis during DNA recombination.
@en
prefLabel
Active site electrostatics pro ...... ysis during DNA recombination.
@en
P2093
P2860
P356
P1433
P1476
Active site electrostatics pro ...... lysis during DNA recombination
@en
P2093
Anna Macieszak
Chien-Hui Ma
Makkuni Jayaram
Piotr Guga
P2860
P304
P356
10.1038/EMBOJ.2009.131
P407
P577
2009-05-14T00:00:00Z