Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.
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The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis.Plk phosphorylation regulates the microtubule-stabilizing protein TCTP.Nek4 status differentially alters sensitivity to distinct microtubule poisonsA novel vascular disrupting agent plinabulin triggers JNK-mediated apoptosis and inhibits angiogenesis in multiple myeloma cellsClinical trials update of the European Organization for Research and Treatment of Cancer Breast Cancer GroupGenome-wide characterisation of the binding repertoire of small molecule drugs.A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancerp53 suppresses structural chromosome instability after mitotic arrest in human cells.BUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD).Nocodazole treatment decreases expression of pluripotency markers Nanog and Oct4 in human embryonic stem cells.Resveratrol attenuates the anticancer efficacy of paclitaxel in human breast cancer cells in vitro and in vivo.JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells.G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells.Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention.The tubulin-binding agent combretastatin A-4-phosphate arrests endothelial cells in mitosis and induces mitotic cell deathp38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest.Inducible overexpression of c-Jun in MCF7 cells causes resistance to vinblastine via inhibition of drug-induced apoptosis and senescence at a step subsequent to mitotic arrest.Depletion of Paraspeckle Protein 1 Enhances Methyl Methanesulfonate-Induced Apoptosis through Mitotic CatastropheTaxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosislemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2.BUB1 mediation of caspase-independent mitotic death determines cell fate.FANCA safeguards interphase and mitosis during hematopoiesis in vivo.Role of the progesterone receptor for paclitaxel resistance in primary breast cancer.Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to Paclitaxel.p53 as a potential predictive factor of response to chemotherapy: feasibility of p53 assessment using a functional test in yeast from trucut biopsies in breast cancer patients.Potent inhibition of tumor survival in vivo by beta-lapachone plus taxol: combining drugs imposes different artificial checkpoints.Paclitaxel gelatin nanoparticles for intravesical bladder cancer therapyShort-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burdenRole of activating transcription factor 3 on TAp73 stability and apoptosis in paclitaxel-treated cervical cancer cells.Moscatilin induces apoptosis and mitotic catastrophe in human esophageal cancer cells.Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity.Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer.Role of prolonged mitotic checkpoint activation in the formation and treatment of cancer.STAT3 is required for MiR-17-5p-mediated sensitization to chemotherapy-induced apoptosis in breast cancer cellsCytoskeleton targeting value in prostate cancer treatment.Src tyrosine kinase augments taxotere-induced apoptosis through enhanced expression and phosphorylation of Bcl-2.Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells.Mesenchymal stromal cells loaded with paclitaxel induce cytotoxic damage in glioblastoma brain xenografts.Cell death response to anti-mitotic drug treatment in cell culture, mouse tumor model and the clinic
P2860
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P2860
Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.
@en
type
label
Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.
@en
prefLabel
Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.
@en
P2093
P2860
P356
P1433
P1476
Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway
@en
P2093
P2860
P2888
P304
P356
10.1007/BF03401588
P407
P577
1995-07-01T00:00:00Z