p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest. - Wikidata - wikimedia - TriplyDB

p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest.

p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest.

http://www.wikidata.org/entity/Q35153630

about

Synergistic antitumor activity of oncolytic reovirus and chemotherapeutic agents in non-small cell lung cancer cells A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons p21-activated kinase signaling in breast cancer The Potential of Vitamin D-Regulated Intracellular Signaling Pathways as Targets for Myeloid Leukemia Therapy Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in HeLa cells p38α MAP Kinase C-Terminal Domain Binding Pocket Characterized by Crystallographic and Computational Analyses JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions Molecular pathways: targeting p21-activated kinase 1 signaling in cancer--opportunities, challenges, and limitations Inhibition of p38 MAPK suppresses inflammatory cytokine induction by etoposide, 5-fluorouracil, and doxorubicin without affecting tumoricidal activity Securin enhances the anti-cancer effects of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075) in human colorectal cancer cells Thymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROS Mutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathway miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells P38 mitogen-activated protein kinase activity is required during mitosis for timely satisfaction of the mitotic checkpoint but not for the fidelity of chromosome segregation.Hydroxyurea exposure triggers tissue-specific activation of p38 mitogen-activated protein kinase signaling and the DNA damage response in organogenesis-stage mouse embryos.Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway Activation of the AMP-activated protein kinase-p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in p53-mutant mouse mammary tumor cells.Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells A small molecule, MTBT, prevents cancer cell growth by activating p38 MAPK.P38α MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism.H3S28 phosphorylation is a hallmark of the transcriptional response to cellular stress.Association of the epithelial-to-mesenchymal transition phenotype with responsiveness to the p21-activated kinase inhibitor, PF-3758309, in colon cancer models.PAK1 as a therapeutic target.The bone marrow microenvironment as a sanctuary for minimal residual disease in CML.Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis.Wild chrysanthemum extract prevents UVB radiation-induced acute cell death and photoaging.Spindle checkpoint function and cellular sensitivity to antimitotic drugs.p38 MAP kinase mediates arsenite-induced apoptosis through FOXO3a activation and induction of Bim transcription.Vitamin E succinate induces NAG-1 expression in a p38 kinase-dependent mechanism Deoxyelephantopin impairs growth of cervical carcinoma SiHa cells and induces apoptosis by targeting multiple molecular signaling pathways.The response to PAK1 inhibitor IPA3 distinguishes between cancer cells with mutations in BRAF and Ras oncogenes.p38 inhibitor SB203580 sensitizes the resveratrol-induced apoptosis in human lung adenocarcinoma (A549) cells.Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin.Translocation and oligomerization of Bax is regulated independently by activation of p38 MAPK and caspase-2 during MN9D dopaminergic neurodegeneration.Caffeine promotes apoptosis in mitotic spindle checkpoint-arrested cells.Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim.P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli.Response of human cells to desiccation: comparison with hyperosmotic stress response.Deoxyarbutin displays antitumour activity against melanoma in vitro and in vivo through a p38-mediated mitochondria associated apoptotic pathway.

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P2860

p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest.

http://www.wikidata.org/entity/Q35153630

description

2003 nî lūn-bûn

@nan

2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

p38 Mitogen-activated protein ...... c drug-induced mitotic arrest.

@ast

p38 Mitogen-activated protein ...... c drug-induced mitotic arrest.

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type

label

p38 Mitogen-activated protein ...... c drug-induced mitotic arrest.

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p38 Mitogen-activated protein ...... c drug-induced mitotic arrest.

@en

prefLabel

p38 Mitogen-activated protein ...... c drug-induced mitotic arrest.

@ast

p38 Mitogen-activated protein ...... c drug-induced mitotic arrest.

@en

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MBC.E02-10-0653

P1433

Molecular Biology of the Cell

P1476

p38 Mitogen-activated protein ...... c drug-induced mitotic arrest.

@en

P2093

Jonathan L Blank

http://www.w3.org/2001/XMLSchema#string

Karl Deacon

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Pratibha Mistry

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Rajnikant Patel

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P2860

Identification of a human mitotic checkpoint gene: hsMAD2

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

Conformation of the Bax C-terminus regulates subcellular location and cell death

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

Movement of Bax from the cytosol to mitochondria during apoptosis

p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis

Pak to the future

MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases

BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival

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2071-2087

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scholarly article

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10.1091/MBC.E02-10-0653

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5

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14

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Jonathan Chernoff

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2003-01-26T00:00:00Z

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10712436

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12802076

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165098

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