Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response.
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Efficient class II major histocompatibility complex presentation of endogenously synthesized hepatitis C virus core protein by Epstein-Barr virus-transformed B-lymphoblastoid cell lines to CD4(+) T cellsDeficiency of small GTPase Rac2 affects T cell activationDNA encoding an HIV-1 Gag/human lysosome-associated membrane protein-1 chimera elicits a broad cellular and humoral immune response in Rhesus macaques.The antigen presentation function of bone marrow-derived mast cells is spatiotemporally restricted to a subset expressing high levels of cell surface FcepsilonRI and MHC IIImmune mechanisms of childhood asthmaRegulation of HIV-Gag expression and targeting to the endolysosomal/secretory pathway by the luminal domain of lysosomal-associated membrane protein (LAMP-1) enhance Gag-specific immune response.CD4 T-cell memory can persist in the absence of class II.Interactions between double positive thymocytes and high affinity ligands presented by cortical epithelial cells generate double negative thymocytes with T cell regulatory activity.Proinflammatory adjuvants enhance the cognate helper activity of aged CD4 T cellsIntercellular adhesion molecule-1 inhibits interleukin 4 production by naive T cellsThe effect of age on the cognate function of CD4+ T cells.Rapid default transition of CD4 T cell effectors to functional memory cellsDirect and regulated interaction of integrin alphaEbeta7 with E-cadherin.The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartmentsAntigen-independent changes in naive CD4 T cells with aging.Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice.In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes.Distinct costimulatory molecules are required for the induction of effector and memory cytotoxic T lymphocytes.Transferable anergy: superantigen treatment induces CD4+ T cell tolerance that is reversible and requires CD4-CD8- cells and interferon gammaAge-related defects in CD4 T cell cognate helper function lead to reductions in humoral responsesCD28-independent induction of T helper cells and immunoglobulin class switches requires costimulation by the heat-stable antigen.Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigenCD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza.Bone marrow precursor cells from aged mice generate CD4 T cells that function well in primary and memory responsesSuppression of established experimental autoimmune uveitis by anti-LFA-1alpha Ab.Transfected Drosophila cells as a probe for defining the minimal requirements for stimulating unprimed CD8+ T cellsInflammatory cytokines overcome age-related defects in CD4 T cell responses in vivoICAM-1-based rabies virus vaccine shows increased infection and activation of primary murine B cells in vitro and enhanced antibody titers in-vivo.LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapseRegulation of CD4+ T-cell contraction during pathogen challengeA viral protein that selectively downregulates ICAM-1 and B7-2 and modulates T cell costimulationThe Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance.T cell adhesion and cytolysis of pancreatic cancer cells: a role for E-cadherin in immunotherapy?Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cellsIntegrins Modulate T Cell Receptor Signaling by Constraining Actin Flow at the Immunological Synapse.LFA-1 in T Cell Migration and Differentiation.Cytotoxic T lymphocyte-associated antigen-4 inhibits integrin-mediated stimulation
P2860
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P2860
Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response.
description
1995 nî lūn-bûn
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1995年の論文
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年學術文章
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1995年學術文章
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1995年學術文章
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name
Costimulatory requirements of ...... required for optimum response.
@en
type
label
Costimulatory requirements of ...... required for optimum response.
@en
prefLabel
Costimulatory requirements of ...... required for optimum response.
@en
P2093
P1476
Costimulatory requirements of ...... required for optimum response
@en
P2093
P407
P577
1995-07-01T00:00:00Z