The activation-resistant conformation of recombinant human plasminogen is stabilized by basic residues in the amino-terminal hinge region.

The activation-resistant conformation of recombinant human plasminogen is stabilized by basic residues in the amino-terminal hinge region.

Item
http://www.wikidata.org/entity/Q41333455
Crystal structure of the native plasminogen reveals an activation-resistant compact conformationNew insights into the role of Plg-RKT in macrophage recruitment.Expression of plasminogen-related gene B varies among normal tissues and increases in cancer tissues.Fibrin-targeted plasminogen activation by plasminogen activator, PadA, from Streptococcus dysgalactiae.Monoclonal antibodies detect receptor-induced binding sites in Glu-plasminogen.Bacterial plasminogen receptors utilize host plasminogen system for effective invasion and dissemination.A high affinity interaction of plasminogen with fibrin is not essential for efficient activation by tissue-type plasminogen activatorEvidence that the conformation of unliganded human plasminogen is maintained via an intramolecular interaction between the lysine-binding site of kringle 5 and the N-terminal peptide.Lysine-50 is a likely site for anchoring the plasminogen N-terminal peptide to lysine-binding kringles.Conversion of Glu-plasminogen to Lys-plasminogen is necessary for optimal stimulation of plasminogen activation on the endothelial cell surface.Coupling of conformational and proteolytic activation in the kinetic mechanism of plasminogen activation by streptokinase.Resolution of conformational activation in the kinetic mechanism of plasminogen activation by streptokinase.Plasminogen-binding proteins as an evasion mechanism of the host's innate immunity in infectious diseases
P2860

The activation-resistant conformation of recombinant human plasminogen is stabilized by basic residues in the amino-terminal hinge region.

Item
http://www.wikidata.org/entity/Q41333455
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
The activation-resistant confo ...... e amino-terminal hinge region.
@en
type
label
The activation-resistant confo ...... e amino-terminal hinge region.
@en
prefLabel
The activation-resistant confo ...... e amino-terminal hinge region.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
The activation-resistant confo ...... e amino-terminal hinge region.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698