Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury. - Wikidata - wikimedia - TriplyDB

Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.

Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.

http://www.wikidata.org/entity/Q41457946

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ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury NLRP3 inflammasome and its inhibitors: a review Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders Targets for Ibrutinib Beyond B Cell Malignancies Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.Anti-Apoptotic and Pro-Survival Effect of Alpinate Oxyphyllae Fructus (AOF) in a d-Galactose-Induced Aging Heart.NLRP3 Deficiency Reduces Macrophage Interleukin-10 Production and Enhances the Susceptibility to Doxorubicin-induced Cardiotoxicity.Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB/STAT3 pathway after ischemic stroke in mice.Post-translational regulation of inflammasomes.Intestinal Autophagy and Its Pharmacological Control in Inflammatory Bowel Disease.Endogenous recovery after brain damage: molecular mechanisms that balance neuronal life/death fate.Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy.Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke.NLRP3 inflammasome: a promising target in ischemic stroke.Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation.Inflammasomes link vascular disease with neuroinflammation and brain disorders.A brain in flame; do inflammasomes and pyroptosis influence stroke pathology?The function of NOD-like receptors in central nervous system diseases.Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux Protein kinase D at the Golgi controls NLRP3 inflammasome activation.Invasive aspergillosis related to ibrutinib therapy for chronic lymphocytic leukemia.ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation.Therapeutic Potential of Intravenous Immunoglobulin in Acute Brain Injury.Posttranslational Modification Control of Inflammatory Signaling.The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein.BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.Bruton's Tyrosine Kinase: An Emerging Key Player in Innate Immunity.Highly selective inhibition of Bruton's tyrosine kinase attenuates skin and brain disease in murine lupus.Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice.The NLRP3 Inflammasome: An Important Driver of Neuroinflammation in Hemorrhagic Stroke.Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis.Role of Bruton's tyrosine kinase in B cells and malignancies.Call for Action: Invasive Fungal Infections Associated With Ibrutinib and Other Small Molecule Kinase Inhibitors Targeting Immune Signaling Pathways.MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.Immune responses in stroke: how the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?Artemisia Extract Suppresses NLRP3 and AIM2 Inflammasome Activation by Inhibition of ASC Phosphorylation.Inhibiting Bruton's Tyrosine Kinase Rescues Mice from Lethal Influenza Induced Acute Lung Injury.

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P2860

Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.

http://www.wikidata.org/entity/Q41457946

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Bruton's tyrosine kinase is es ...... tes to ischaemic brain injury.

@en

type

label

Bruton's tyrosine kinase is es ...... tes to ischaemic brain injury.

@en

prefLabel

Bruton's tyrosine kinase is es ...... tes to ischaemic brain injury.

@en

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Nature Communications

P1476

Bruton's tyrosine kinase is es ...... tes to ischaemic brain injury.

@en

P2093

Akihiko Yoshimura

http://www.w3.org/2001/XMLSchema#string

Masahiro Okada

http://www.w3.org/2001/XMLSchema#string

Minako Ito

http://www.w3.org/2001/XMLSchema#string

Rimpei Morita

http://www.w3.org/2001/XMLSchema#string

Ritsuko Komine

http://www.w3.org/2001/XMLSchema#string

Takashi Shichita

http://www.w3.org/2001/XMLSchema#string

Yoshiko Noguchi

http://www.w3.org/2001/XMLSchema#string

P2860

The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells

Novel role of PKR in inflammasome activation and HMGB1 release

The inflammasomes

Active caspase-1 is a regulator of unconventional protein secretion

GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals

Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death

Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA)

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10.1038/NCOMMS8360

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6

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2015-06-10T00:00:00Z

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278044974

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26059659

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1410.0914

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4490404

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