Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response.
about
The 20th anniversary of interleukin-2 therapy: bimodal role explaining longstanding random induction of complete clinical responsesImplications of Epigenetic Variability within a Cell Population for "Cell Type" ClassificationHeterogeneity in immune responses: from populations to single cellsDaclizumab therapy for multiple sclerosisIL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8(+) T cell-APC: a multiscale modeling studyUnderstanding HIV latency: the road to an HIV cureIntegrating signals from the T-cell receptor and the interleukin-2 receptorExploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosisPhosphorylation site dynamics of early T-cell receptor signalingMultiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reactionSingle-cell transcriptomics reveals bimodality in expression and splicing in immune cellsRule-based multi-level modeling of cell biological systemsThe effects of interleukin-2 on immune response regulation.Polyfunctional responses by human T cells result from sequential release of cytokines.Desert ants achieve reliable recruitment across noisy interactionsThe efficacy and safety of daclizumab and its potential role in the treatment of multiple sclerosis.Stochastic sensitivity analysis and kernel inference via distributional data.A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activityModeling the receptor pharmacology, pharmacokinetics, and pharmacodynamics of NKTR-214, a kinetically-controlled interleukin-2 (IL2) receptor agonist for cancer immunotherapy.An in silico modeling approach to understanding the dynamics of sarcoidosisEffector and naturally occurring regulatory T cells display no abnormalities in activation induced cell death in NOD miceA quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model.Balancing speed and accuracy of polyclonal T cell activation: a role for extracellular feedback.Concurrent interaction of DCs with CD4(+) and CD8(+) T cells improves secondary CTL expansion: It takes three to tango.Systems modeling of molecular mechanisms controlling cytokine-driven CD4+ T cell differentiation and phenotype plasticity.Transcriptional regulation by nicotine in dopaminergic neurons.Mechanistic model of natural killer cell proliferative response to IL-15 receptor stimulationSocial interaction in synthetic and natural microbial communities.Using an adaptive gene network model for self-organizing multicellular behavior.Sending mixed messages for cell population control.Foxp3⁺ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis.Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.Single-cell RNA-seq reveals dynamic paracrine control of cellular variation.Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction.Central role for interleukin-2 in type 1 diabetes.Three-Dimensional Gradients of Cytokine Signaling between T Cells.PDE/ODE modeling and simulation to determine the role of diffusion in long-term and -range cellular signaling.T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar AntigensQuorum-Sensing in CD4(+) T Cell Homeostasis: A Hypothesis and a Model.Design principles of cell circuits with paradoxical components.
P2860
Q24616434-8BF78560-779B-4C9D-957C-6185FE0C2C52Q26770736-4C705957-C339-41E2-930E-23B426DBE66DQ27013828-69E50CDB-A177-4B98-93EC-E5E353FDB755Q27022517-9CCE2328-E154-4640-8E34-7292F4F3BD4EQ27304738-ABA01D18-CD6D-490F-9927-ABE37931E389Q28085296-042DFE88-C033-42A1-AA9B-B22D71FBA64EQ28476433-648ED837-7847-4C96-A5D1-51FCCA9E2660Q28483276-CFEC3769-3C06-4C03-954A-75FC7774C89CQ28542511-A5A63FEE-1DA8-4A38-B6B0-91D1E8387AF6Q28829885-02AE10BC-4683-4DB8-BB6C-282E71C0D984Q29617430-0919C2FE-1AAB-4799-8EFA-AE5C5EDDF0FDQ30082628-7329A260-951D-4250-8F01-31259D828BF0Q30252875-13B60668-1059-457E-B94E-9D1F1439C8A9Q30505101-3B4B3688-06FA-4480-AE16-C2902EC31135Q30538890-E2E9C7BC-564D-4075-90D4-9F0FB543855FQ30730505-82F1CE3A-C1B1-4A28-BCF2-9107555D72DEQ30847351-C845E125-09A1-4141-A339-B890309D4DCEQ33573863-30C38481-0487-4CAE-BF3C-C324430D8811Q33873731-20F56F35-8B70-436F-BB8A-A5A9752DBE26Q33921040-2901BC3B-A3DA-4E6E-A08A-B4B06255B00EQ33955180-054E7718-EB4E-4BC1-B918-AB90D734ACABQ34331673-54AB0712-6C28-427F-AE9B-08E4A938B6BBQ34394210-93C88793-CEF0-4968-A9FA-60D4851AF70CQ34438014-59E74350-68BA-4E96-BBB4-FA6CAAE38BB6Q34671782-387C194D-9110-47E2-BE07-2C3358C669B9Q34933695-AACB465F-7C41-482B-A9F6-90C95807D861Q34998162-76413893-5E3B-45FE-A67A-1D7E56AC7523Q35006971-4F11D1B4-8B74-440E-988D-70FE37D6E730Q35026664-0D8DE46E-439A-4250-9C90-3A47C8A133E2Q35154596-0248997E-D1D6-4872-A355-24B1780FB162Q35172468-D1813ACE-5419-42EB-ACB6-7EA5F0768D72Q35176382-307AD397-F6B0-4377-B1FC-B07F8853F43CQ35185544-85288E30-25DA-4BE9-979A-754CBC93F253Q35204547-6DA8C854-CF9B-4764-8759-C994D1F2AF99Q35612414-5A49A483-7979-477E-9BD9-0ECA8E44787DQ35617695-B2227D11-4BD8-4A24-936A-B26D055E7E1BQ35809882-678E27BB-EEBB-46C1-821D-F04620B416FAQ35893938-A58DF02F-06BC-4628-8F64-AD866B15B6C6Q35988097-6B21F02C-6B0F-438D-8D92-9B49C46FA9A3Q35991400-BC722A1A-F66F-4B57-9382-16702F4C7D39
P2860
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Single-cell quantification of ...... plasticity in immune response.
@en
type
label
Single-cell quantification of ...... plasticity in immune response.
@en
prefLabel
Single-cell quantification of ...... plasticity in immune response.
@en
P2093
P2860
P356
P1476
Single-cell quantification of ...... plasticity in immune response.
@en
P2093
Garrit Jentsch
Grégoire Altan-Bonnet
Jesse W Coward
Karen E Tkach
Kendall A Smith
Matthew M Hathorn
Michael W Sneddon
Ofer Feinerman
P2860
P356
10.1038/MSB.2010.90
P577
2010-11-01T00:00:00Z