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Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

http://www.wikidata.org/entity/Q41473465

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Strategies for Integrated Analysis of Genetic, Epigenetic, and Gene Expression Variation in Cancer: Addressing the Challenges Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine Current concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia Using epigenomics data to predict gene expression in lung cancer.Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia.Genomics of racial and ethnic disparities in childhood acute lymphoblastic leukemia.The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer Epigenetic deregulation in pediatric acute lymphoblastic leukemia.Targeting the 5T4 oncofetal glycoprotein with an antibody drug conjugate (A1mcMMAF) improves survival in patient-derived xenograft models of acute lymphoblastic leukemia.Childhood B-acute lymphoblastic leukemia: a genetic update.A therapeutic trial of decitabine and vorinostat in combination with chemotherapy for relapsed/refractory acute lymphoblastic leukemia.Biology of childhood acute lymphoblastic leukemia.The biology of relapsed acute lymphoblastic leukemia: opportunities for therapeutic interventions.DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia.Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.The Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and Clinical Outcome in Acute Lymphoblastic Leukemia.Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia.Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia Integrated methylome and transcriptome analysis reveals novel regulatory elements in pediatric acute lymphoblastic leukemia.Potential roles of microRNA-29a in the molecular pathophysiology of T-cell acute lymphoblastic leukemia.DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukemia Genomic characterization of childhood acute lymphoblastic leukemia.HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia.The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia.MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia.Chromatin modifiers and the promise of epigenetic therapy in acute leukemia Epigenetic modifications in pediatric acute lymphoblastic leukemia.Pathogenesis and prognostication in acute lymphoblastic leukemia.The roles of AXIN2 in tumorigenesis and epigenetic regulation.Epigenetics in T-cell acute lymphoblastic leukemia.Genomic and pharmacogenetic studies of childhood acute lymphoblastic leukemia.Genomics in acute lymphoblastic leukaemia: insights and treatment implications.Inferring a role for methylation of intergenic DNA in the regulation of genes aberrantly expressed in precursor B-cell acute lymphoblastic leukemia.Epigenetic drug combination overcomes osteoblast-induced chemoprotection in pediatric acute lymphoid leukemia.DNA Methylation Adds Prognostic Value to Minimal Residual Disease Status in Pediatric T-Cell Acute Lymphoblastic Leukemia.Selected miRNA levels are associated with IKZF1 microdeletions in pediatric acute lymphoblastic leukemia.GATA2 regulates the erythropoietin receptor in t(12;21) ALL.Whole-genome DNA methylation characteristics in pediatric precursor B cell acute lymphoblastic leukemia (BCP ALL).MGMT promoter methylation as a potential prognostic marker for acute leukemia.

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Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

http://www.wikidata.org/entity/Q41473465

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

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type

label

Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

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Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

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Journal of Clinical Investigation

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Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

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Anna K Andersson

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Ari Melnick

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James R Downing

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Jason Sotzen

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Letha A Phillips

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Maria E Figueroa

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Shann-Ching Chen

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Yushan Li

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P2860

Bioconductor: open software development for computational biology and bioinformatics

HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Treating childhood acute lymphoblastic leukemia without cranial irradiation

Comparative isoschizomer profiling of cytosine methylation: the HELP assay

IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report.

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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Charles G. Mullighan

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2013-06-10T00:00:00Z

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