A mouse model of the most aggressive subgroup of human medulloblastoma
about
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamicsSmall molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastomaCombined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable diseaseMedulloblastoma stem cells: Promising targets in medulloblastoma therapyThe role of the ubiquitin proteasome system in cerebellar development and medulloblastomaIn vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studiesCytomegalovirus in human brain tumors: Role in pathogenesis and potential treatment optionsCross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenanceCasein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis.A Proteogenomic Approach to Understanding MYC Function in Metastatic Medulloblastoma TumorsThe Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup IdentityIn vivo Mn-enhanced MRI for early tumor detection and growth rate analysis in a mouse medulloblastoma model.Deriving therapies for children with primary CNS tumors using pharmacokinetic modeling and simulation of cerebral microdialysis dataNOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma.Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma.The prenatal origins of cancerThe genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade gliomaMYC Deregulation in Primary Human Cancers.Mutation and expression analysis in medulloblastoma yields prognostic variants and a putative mechanism of disease for i17q tumors.Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development.Epigenetic states of cells of origin and tumor evolution drive tumor-initiating cell phenotype and tumor heterogeneity.Children's Oncology Group's 2013 blueprint for research: central nervous system tumors.Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.Orthotopic models of pediatric brain tumors in zebrafishGlial progenitors as targets for transformation in glioma.Deregulated proliferation and differentiation in brain tumors.Medulloblastoma subgroups remain stable across primary and metastatic compartments.Molecular subgroups of medulloblastoma.Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma.Molecular and in vivo characterization of cancer-propagating cells derived from MYCN-dependent medulloblastomaGene expression analyses of the spatio-temporal relationships of human medulloblastoma subgroups during early human neurogenesisMechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma.Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modellingSomatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice.Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-propertiesN-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells.Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.BarTeL, a Genetically Versatile, Bioluminescent and Granule Neuron Precursor-Targeted Mouse Model for Medulloblastoma.Genetic and molecular alterations across medulloblastoma subgroups
P2860
Q24294672-C5D760B3-83CA-4B44-AF70-A5243B2333A3Q24296639-B5BF7C70-BD7C-4F9F-AC20-F44C7381E0EEQ24310764-940F0B60-58E4-4A02-8456-44EABBEA59D8Q26750427-FC0A9951-DE62-44D6-B171-E23C3B2DF92BQ26782159-BD8AF6D4-BD7E-4A47-BBC7-DC28AF6AE59CQ26820289-31E4D382-3CCC-4BA6-AFE1-916AE16FC344Q26996612-10DF2F93-501C-4B84-978A-9C115829F40EQ27310060-D3A3FF8E-45DA-4525-914A-EFCB066271A5Q27320896-0405586D-3C54-4AD9-9699-5317AF87EEA5Q28071574-01D5D5EF-C20E-4532-B509-A671CED96ACCQ28114769-3E79A07B-5C27-48A1-A86A-6B7BD6CB8ADAQ30618694-14F84DE3-3A4F-4CB9-AA50-B55F2FC35C57Q30700231-5C25BDE8-C8B5-41E5-8FAE-CACB7FF5D544Q33622402-8FA9CC49-C0E9-464C-A9BE-8F34EDA8F9AFQ33633473-ADA637D4-8600-4C71-AA65-E72362190491Q33697463-E41426E4-8983-4840-A349-63582DC85290Q33751426-B1C9DFB9-A01E-4502-8817-77329581D8A7Q33836755-3E8B7318-FE4A-4727-8818-45E98C1638D5Q34108929-B6E81D4F-C20A-4280-B4EB-9DCAE848D4BEQ34131951-DE8E9BBC-C587-4C3F-9E48-F670B1652F4EQ34135305-F12A1FDA-E59B-45BC-82D8-7BAA0CDFB964Q34285237-CD8FDEDF-94BF-47E6-B37B-794EC7873253Q34362028-056F72D5-B4A4-4149-8F0D-91157A29F6BEQ34381550-1E0DF3A4-6C57-48BA-9B78-73C805B42029Q34735661-84225295-B471-4820-89F8-80811A7BD1F9Q34859989-4285E0D3-7644-4D05-B306-27EC4962267BQ35099027-62FDA28D-0ED1-4AD3-B9AC-481D6FFD5AF0Q35101347-C6AD3665-BE95-468C-A9FB-D8E0BB8C2EF0Q35135650-EB1D8BB4-1E23-4A26-B77B-5BE85F2EB86FQ35192672-F1620F5A-8222-4D59-9F3B-279498547606Q35440212-994F1584-94A0-4D11-9D1A-04156164DB35Q35550246-B0F16BCD-2D09-49E0-9406-DA3C3DA0A28BQ35742331-08CFEEAF-BA23-4A7C-9583-EB1E87E1EE46Q35827814-FB98EA4E-B72C-491C-AD20-6B10CF80372BQ35920823-F40DD271-D40E-41BA-A2D1-DF48612BE4A1Q35925281-E78FBAA7-F33D-4711-8C21-3CE716244578Q35980945-9447A53B-23EC-4F35-8132-9EDD0EC016D0Q35989886-FC7384F8-C3CB-43E4-B67E-888204E8D360Q36054158-97BF899C-9767-46B6-A906-5BA13F41B7C0Q36142459-6D5DB177-71EE-40A4-8637-E5BACDE5AEAC
P2860
A mouse model of the most aggressive subgroup of human medulloblastoma
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A mouse model of the most aggressive subgroup of human medulloblastoma
@en
type
label
A mouse model of the most aggressive subgroup of human medulloblastoma
@en
prefLabel
A mouse model of the most aggressive subgroup of human medulloblastoma
@en
P2093
P2860
P50
P1433
P1476
A mouse model of the most aggressive subgroup of human medulloblastoma
@en
P2093
Cuilan Gao
Daisuke Kawauchi
David Finkelstein
David W Ellison
Jerold Rehg
Paul Gibson
Richard J Gilbertson
Tamar Uziel
P2860
P304
P356
10.1016/J.CCR.2011.12.023
P577
2012-02-01T00:00:00Z