Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation.
about
Echoes of the embryo: using the developmental biology toolkit to study cancerStem cells in genetically-engineered mouse models of prostate cancerThe many ways to make a luminal cell and a prostate cancer cellRoles for Hedgehog signaling in adult organ homeostasis and repairBiologic and clinical significance of androgen receptor variants in castration resistant prostate cancerNotch signaling in prostate cancer: a moving targetQuantitative lineage tracing strategies to resolve multipotency in tissue-specific stem cellsBidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneityCell-of-Origin of Cancer versus Cancer Stem Cells: Assays and InterpretationsOrganoid development in cancer genome discoveryLoss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinomaSonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration.Regulation of the pentose phosphate pathway by an androgen receptor-mTOR-mediated mechanism and its role in prostate cancer cell growth.Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.Mouse models of prostate cancer: picking the best model for the question.The prostate basal cell (BC) heterogeneity and the p63-positive BC differentiation spectrum in mice.Luminal cells are favored as the cell of origin for prostate cancerSingle luminal epithelial progenitors can generate prostate organoids in culture.Estrogen receptor β activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations.Molecular pathways and targets in prostate cancerIdentification of CD166 as a surface marker for enriching prostate stem/progenitor and cancer initiating cellsProstate epithelial stem and progenitor cells.Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathwaysHuman prostate side population cells demonstrate stem cell properties in recombination with urogenital sinus mesenchyme.Induced pluripotency of human prostatic epithelial cells.Prostate adenocarcinomas aberrantly expressing p63 are molecularly distinct from usual-type prostatic adenocarcinomas.Hedgehog signaling in prostate epithelial-mesenchymal growth regulation.Enhanced enrichment of prostate cancer stem-like cells with miniaturized 3D culture in liquid core-hydrogel shell microcapsulesDifferential gene expression profiling of functionally and developmentally distinct human prostate epithelial populationsMulti-Drug Resistance ABC Transporter Inhibition Enhances Murine Ventral Prostate Stem/Progenitor Cell Differentiation.Cell kinetic studies fail to identify sequentially proliferating progenitors as the major source of epithelial renewal in the adult murine prostate.Pten Regulates Epithelial Cytodifferentiation during Prostate Development.Prostate Sphere-forming Stem Cells Are Derived from the P63-expressing Basal Compartment.Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment.Stem cell plasticity. Plasticity of epithelial stem cells in tissue regenerationN-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells.A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon.A Long-Lived Luminal Subpopulation Enriched with Alveolar Progenitors Serves as Cellular Origin of Heterogeneous Mammary Tumors.PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary glandβ4 Integrin signaling induces expansion of prostate tumor progenitors
P2860
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P2860
Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Adult murine prostate basal an ...... or prostate cancer initiation.
@en
type
label
Adult murine prostate basal an ...... or prostate cancer initiation.
@en
prefLabel
Adult murine prostate basal an ...... or prostate cancer initiation.
@en
P2093
P2860
P1433
P1476
Adult murine prostate basal an ...... or prostate cancer initiation.
@en
P2093
Boyu Zhang
Michael Ittmann
Nahyun Choi
P2860
P304
P356
10.1016/J.CCR.2012.01.005
P577
2012-02-01T00:00:00Z