Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.
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Pandemic Threat Posed by Avian Influenza A VirusesFurin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteinsCytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathwayTwo independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furinIntracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surfaceNovel avian influenza H7N3 strain outbreak, British ColumbiaIsolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytesInfluenza A virus neuraminidase limits viral superinfectionRab11 is required for trans-golgi network-to-plasma membrane transport and a preferential target for GDP dissociation inhibitorProteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epitheliumThe role of eukaryotic subtilisin-like endoproteases for the activation of human immunodeficiency virus glycoproteins in natural host cellsProteolytic activation of tick-borne encephalitis virus by furinOligomerization-dependent folding of the membrane fusion protein of Semliki Forest virusChanging the Protease Specificity for Activation of a Flavivirus, Tick-Borne Encephalitis VirusEbolavirus glycoprotein structure and mechanism of entryInsights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 CleavageDomain Flexibility Modulates the Heterogeneous Assembly Mechanism of Anthrax Toxin Protective AntigenThe ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatusHuman microRNAs profiling in response to influenza A viruses (subtypes pH1N1, H3N2, and H5N1)Inhibition of influenza virus replication by targeting broad host cell pathwaysZoonotic infections with avian influenza A viruses and vaccine preparedness: a game of "mix and match"Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.Molecular evolution of H6 influenza viruses from poultry in Southeastern China: prevalence of H6N1 influenza viruses possessing seven A/Hong Kong/156/97 (H5N1)-like genes in poultry.Progress of small molecular inhibitors in the development of anti-influenza virus agents.Avian-to-human transmission of H9N2 subtype influenza A viruses: relationship between H9N2 and H5N1 human isolates.Virus-specific factors associated with zoonotic and pandemic potential.Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.Molecular determinants of influenza virus pathogenesis in mice.Entry properties and entry inhibitors of a human H7N9 influenza virus.Novel approach to the development of effective H5N1 influenza A virus vaccines: use of M2 cytoplasmic tail mutants.Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses.Genetic Predisposition To Acquire a Polybasic Cleavage Site for Highly Pathogenic Avian Influenza Virus Hemagglutinin.Molecular pathogenesis of H5 highly pathogenic avian influenza: the role of the haemagglutinin cleavage site motifRapid preparation of mutated influenza hemagglutinins for influenza virus pandemic prevention.Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitorsTMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus.The ecology and adaptive evolution of influenza A interspecies transmissionProtective immunity against H5N1 influenza virus by a single dose vaccination with virus-like particlesInhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.Temporal- and strain-specific host microRNA molecular signatures associated with swine-origin H1N1 and avian-origin H7N7 influenza A virus infection.
P2860
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P2860
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Influenza virus hemagglutinin ...... subtilisin-like endoprotease.
@en
type
label
Influenza virus hemagglutinin ...... subtilisin-like endoprotease.
@en
prefLabel
Influenza virus hemagglutinin ...... subtilisin-like endoprotease.
@en
P2093
P2860
P1433
P1476
Influenza virus hemagglutinin ...... subtilisin-like endoprotease.
@en
P2093
A Stieneke-Gröber
H Angliker
P2860
P304
P407
P577
1992-07-01T00:00:00Z