Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones.
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Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furinProprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipaseFurin-mediated processing of Pro-C-type natriuretic peptideInhibition of proteases with enkephalin-analogue inhibitors.Recent developments in inhibiting cysteine and serine proteases.Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitorsOptimization of protease-inhibitor interactions by randomizing adventitious contactsIdentification and characterization of spodoptera frugiperda furin: a thermostable subtilisin-like endopeptidase.Furin is involved in baculovirus envelope fusion protein activation.Proteolytic processing of the Cryptosporidium glycoprotein gp40/15 by human furin and by a parasite-derived furin-like protease activity.Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases.Mutations within the proteolytic cleavage site of the Rous sarcoma virus glycoprotein define a requirement for dibasic residues for intracellular cleavage.Strategies to inhibit viral polyprotein cleavages.Activation of influenza viruses by proteases from host cells and bacteria in the human airway epithelium.Therapeutic uses of furin and its inhibitors: a patent review.The proprotein convertase furin in tumour progression.Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics.Processing of the Borna disease virus glycoprotein gp94 by the subtilisin-like endoprotease furin.Cleavage of influenza a virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases.Proteolytic cleavage of bovine herpesvirus 1 (BHV-1) glycoprotein gB is not necessary for its function in BHV-1 or pseudorabies virus.Type II transmembrane serine proteases as potential target for anti-influenza drug discovery.Furin-mediated cleavage of the feline foamy virus Env leader protein.Tumor necrosis factor-alpha converting enzyme is processed by proprotein-convertases to its mature form which is degraded upon phorbol ester stimulation.Effects of L- and D-REKR amino acid-containing peptides on HIV and SIV envelope glycoprotein precursor maturation and HIV and SIV replication.Effect of alpha-1 antitrypsin Portland variant (alpha 1-PDX) on HIV-1 replication.Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.The synthesis of inhibitors for processing proteinases and their action on the Kex2 proteinase of yeast.Pseudoarginine: synthesis and properties of derivatives of delta-(1-imidazolyl)norvaline.Proteolytic processing of the hepatitis B virus e antigen precursor. Cleavage at two furin consensus sequences.Stretch-induced hypertrophic growth of cardiocytes and processing of brain-type natriuretic peptide are controlled by proprotein-processing endoprotease furin.Engineering a Constrained Peptidic Scaffold towards Potent and Selective Furin Inhibitors.
P2860
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P2860
Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Inhibition of proteolytic acti ...... peptidyl chloroalkyl ketones.
@en
type
label
Inhibition of proteolytic acti ...... peptidyl chloroalkyl ketones.
@en
prefLabel
Inhibition of proteolytic acti ...... peptidyl chloroalkyl ketones.
@en
P2093
P1433
P1476
Inhibition of proteolytic acti ...... peptidyl chloroalkyl ketones.
@en
P2093
P356
10.1016/0042-6822(89)90103-7
P407
P577
1989-09-01T00:00:00Z