The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions.
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Cripto: a novel epidermal growth factor (EGF)-related peptide in mammary gland development and neoplasiaDominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2. Both ErbB-1 and ErbB-2 contribute significantly to tumorigenicityUnique carboxyl-terminal sequences of wild type and alternatively spliced variant forms of transforming growth factor-alpha precursors mediate specific interactions with ErbB4 and ErbB2An RBCC protein implicated in maintenance of steady-state neuregulin receptor levelsLethal congenital contractural syndrome type 2 (LCCS2) is caused by a mutation in ERBB3 (Her3), a modulator of the phosphatidylinositol-3-kinase/Akt pathwayAZU-1: a candidate breast tumor suppressor and biomarker for tumor progressionInhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domainNeuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1Outcome and human epidermal growth factor receptor (HER) 1-4 status in invasive breast carcinomas with proliferation indices evaluated by bromodeoxyuridine labellingPolysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situ hybridization and immunohistochemistry.Tyrosine kinase signalling in breast cancer. Epidermal growth factor receptor: convergence point for signal integration and diversificationPrognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer.EGFR/HER-targeted therapeutics in ovarian cancerSolution structure of the mEGF/TGFalpha44-50 chimeric growth factorStructural analysis of an epidermal growth factor/transforming growth factor-alpha chimera with unique ErbB binding specificityClinical Translation and Validation of a Predictive Biomarker for Patritumab, an Anti-human Epidermal Growth Factor Receptor 3 (HER3) Monoclonal Antibody, in Patients With Advanced Non-small Cell Lung Cancer.HER2 aberrations and heterogeneity in cancers of the digestive system: Implications for pathologists and gastroenterologistsIntra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatasesErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomasRYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptorHeregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinaseRegulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomesThe ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cellsProtein tyrosine phosphatase, PTP1B, expression and activity in rat corneal endothelial cellsAmphiregulin is a novel growth factor involved in normal bone development and in the cellular response to parathyroid hormone stimulationChanges in ErbB2 (her-2/neu), ErbB3, and ErbB4 during growth, differentiation, and apoptosis of normal rat mammary epithelial cellsErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactationA dual role of erbB2 in myelination and in expansion of the schwann cell precursor poolControlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimersc-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptorThe tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression.ErbB3 (HER3) interaction with the p85 regulatory subunit of phosphoinositide 3-kinase.Src family kinases and HER2 interactions in human breast cancer cell growth and survival.Open-label, phase II, multicenter, randomized study of the efficacy and safety of two dose levels of Pertuzumab, a human epidermal growth factor receptor 2 dimerization inhibitor, in patients with human epidermal growth factor receptor 2-negative meErbB expression: the mouse inner ear and maturation of the mitogenic response to heregulin.Stepwise movements in vesicle transport of HER2 by motor proteins in living cellsAqueous and micelle-bound structural characterization of the epidermal growth factor receptor juxtamembrane domain containing basolateral sorting motifs.Selection of peptides and synthesis of pentameric peptabody molecules reacting specifically with ErbB-2 receptor.The inhibition of lung cancer cell growth by intracellular immunization with LC-1 ScFv.
P2860
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P2860
The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The ErbB signaling network in ...... ligand-receptor interactions.
@en
type
label
The ErbB signaling network in ...... ligand-receptor interactions.
@en
prefLabel
The ErbB signaling network in ...... ligand-receptor interactions.
@en
P1433
P1476
The ErbB signaling network in ...... ligand-receptor interactions.
@en
P2093
P356
10.1016/S0014-5793(97)00412-2
P407
P577
1997-06-01T00:00:00Z