Src family kinases and HER2 interactions in human breast cancer cell growth and survival. - Wikidata - wikimedia - TriplyDB

Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

http://www.wikidata.org/entity/Q30307291

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p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2 Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinase Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells Dok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk.SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells.Differential regulation of EphA2 in normal and malignant cells Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90 HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer The Transmodulation of HER2 and EGFR by Substance P in Breast Cancer Cells Requires c-Src and Metalloproteinase Activation Evasion mechanisms to Igf1r inhibition in rhabdomyosarcoma Epidermal growth factor-receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models.Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells.Pathways to tamoxifen resistance.c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function.Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells.Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling.Inhibition of Integrin-HER2 signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer.Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell lines DHHC20: a human palmitoyl acyltransferase that causes cellular transformation Herceptin conjugates linked by EDC boost direct tumor cell death via programmed tumor cell necrosis.Src inhibitors in the treatment of metastatic bone disease: rationale and clinical data Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents.p27: a barometer of signaling deregulation and potential predictor of response to targeted therapies.The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis Small molecule tyrosine kinase inhibitors: clinical development of anticancer agents.SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment FHIT-proteasome degradation caused by mitogenic stimulation of the EGF receptor family in cancer cells.A novel phosphatidic acid-protein-tyrosine phosphatase D2 axis is essential for ERBB2 signaling in mammary epithelial cells.Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition.Update on the molecular profile of the MDA-MB-453 cell line as a model for apocrine breast carcinoma studies Cancer metastasis therapeutic targets and drug discovery: emerging small-molecule protein kinase inhibitors.Loss of Hsp90 association up-regulates Src-dependent ErbB2 activity.Src promotes estrogen-dependent estrogen receptor alpha proteolysis in human breast cancer Physical Intimacy of Breast Cancer Cells with Mesenchymal Stem Cells Elicits Trastuzumab Resistance through Src Activation

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P2860

Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

http://www.wikidata.org/entity/Q30307291

description

2001 nî lūn-bûn

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2001 թուականի Մարտին հրատարակուած գիտական յօդուած

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2001 թվականի մարտին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

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Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

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type

label

Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

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Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

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Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

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Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

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Src family kinases and HER2 interactions in human breast cancer cell growth and survival.

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Belsches-Jablonski AP

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Biscardi JS

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Parsons SJ

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Peavy DR

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Romney DA

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Tice DA

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P2860

Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4

Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3

Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

Distinct tyrosine autophosphorylation sites negatively and positively modulate neu-mediated transformation

Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

Involvement of pp60c-src with two major signaling pathways in human breast cancer.

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1465-1475

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10.1038/SJ.ONC.1204205

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12

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20

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12020705

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1020109614

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11313890

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