Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor.
about
Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infectionIdentification of a P2X7 receptor in GH(4)C(1) rat pituitary cells: a potential target for a bioactive substance produced by Pfiesteria piscicida.Microfluorimetric analysis of a purinergic receptor (P2X7) in GH4C1 rat pituitary cells: effects of a bioactive substance produced by Pfiesteria piscicida.Inhibition of chemokine expression in rat inflamed paws by systemic use of the antihyperalgesic oxidized ATPInterleukin-1β has trophic effects in microglia and its release is mediated by P2X7R pore.P2X7 receptors stimulate AKT phosphorylation in astrocytesExtracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cellsNovel data point to a broader mechanism of action of oxidized ATP: the P2X7 receptor is not the only targetPhagocytic cell killing mediated by secreted cytotoxic factors of Vibrio choleraeEnhancement of antigen-specific Treg vaccination in vivo.Activation of P2X receptors induces apoptosis in human retinal pigment epitheliumNAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal deathP2Z-Independent and P2Z receptor-mediated macrophage killing by Pseudomonas aeruginosa isolated from cystic fibrosis patients.In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1 beta in the murine brainPurinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: roles in the outcome of excitotoxic brain injury.Characterization of P2X7R and its function in the macrophages of ayu, Plecoglossus altivelisPurinergic signaling is required for fluid shear stress-induced NF-κB translocation in osteoblastsOxidized ATP protection against anthrax lethal toxin.P2X(7) receptor and polykarion formation.Bromoenol lactone enhances the permeabilization of rat submandibular acinar cells by P2X7 agonists.Multiple effects of trichloroethanol on calcium handling in rat submandibular acinar cells.Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor-independent mechanisms.Nonspecific cytotoxic cell antimicrobial protein (NCAMP-1): a novel alarmin ligand identified in zebrafish.Cell-autonomous regulation of hematopoietic stem cell cycling activity by ATP.Activation and regulation of purinergic P2X receptor channelsCell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalanceActivation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation.The purinergic P2Z receptor of human macrophage cells. Characterization and possible physiological role.The Beneficial Effects of P2X7 Antagonism in Rats with Bile Duct Ligation-induced Cirrhosis.The P2Z-purinoceptor of human lymphocytes: actions of nucleotide agonists and irreversible inhibition by oxidized ATP.Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU).P2X(7) receptor: Death or life?Spontaneous cell fusion in macrophage cultures expressing high levels of the P2Z/P2X7 receptorPurinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin.Purinergic receptors are required for HIV-1 infection of primary human macrophages.Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine wayEffect of the purinergic inhibitor oxidized ATP in a model of islet allograft rejection.Ion efflux and influenza infection trigger NLRP3 inflammasome signaling in human dendritic cellsDiscovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states
P2860
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P2860
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor.
@en
type
label
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor.
@en
prefLabel
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor.
@en
P2093
P1476
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor.
@en
P2093
P304
P407
P577
1993-04-01T00:00:00Z