Human P-glycoprotein transports cyclosporin A and FK506.
about
A Rationale for Age-Adapted Immunosuppression in Organ TransplantationAntifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug actionCyclosporin A reduces canalicular membrane fluidity and regulates transporter function in ratsABCB1 1199G>A genetic polymorphism (Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell linesPersonalized tacrolimus dose requirement by CYP3A5 but not ABCB1 or ACE genotyping in both recipient and donor after pediatric liver transplantationInterference of antibacterial agents with phagocyte functions: immunomodulation or "immuno-fairy tales"?Intracellular distribution of anthracyclines in drug resistant cells.Donor age and renal P-glycoprotein expression associate with chronic histological damage in renal allografts.Determination of the most influential sources of variability in tacrolimus trough blood concentrations in adult liver transplant recipients: a bottom-up approachIncidence of genetic polymorphisms involved in lipid metabolism among Chinese patients with osteonecrosis of the femoral headSex Differences in the Blood Concentration of Tacrolimus in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients with CYP3A5*3/*3The correlation between the expression of genes involved in drug metabolism and the blood level of tacrolimus in liver transplant receiptsLung transplantation in telomerase mutation carriers with pulmonary fibrosis.Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism.PharmGKB summary: cyclosporine and tacrolimus pathwaysMacrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycinRelationship of CYP3A5 genotype and ABCB1 diplotype to tacrolimus disposition in Brazilian kidney transplant patientsCalcineurin is essential for survival during membrane stress in Candida albicans.Immunosuppressive interactions among calcium channel antagonists and selected corticosteroids and macrolides using human whole blood lymphocytes.Moxidectin and the avermectins: Consanguinity but not identity.Different influences on tacrolimus pharmacokinetics by coadministrations of zhi ke and zhi shi in ratsAbcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos.The earliest trough concentration predicts the dose of tacrolimus required for remission induction therapy in ulcerative colitis patientsIdentification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators.MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males.Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes.Progressive decline in tacrolimus clearance after renal transplantation is partially explained by decreasing CYP3A4 activity and increasing haematocritInteraction of tamoxifen with the multidrug resistance P-glycoprotein.Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson's disease.Pharmacokinetics of tacrolimus during pregnancyPersonalizing initial calcineurin inhibitor dosing by adjusting to donor CYP3A-status in liver transplant patients.The pregnane X receptor in tuberculosis therapeutics.Novel polymorphisms associated with tacrolimus trough concentrations: results from a multicenter kidney transplant consortiumFunctional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520.Fungal lipopeptide mating pheromones: a model system for the study of protein prenylationInterpreting tacrolimus concentrations during pregnancy and postpartum.ABCB1 polymorphisms may have a minor effect on ciclosporin blood concentrations in myasthenia gravis patientsEndomyocardial, intralymphocyte, and whole blood concentrations of ciclosporin A in heart transplant recipients.Multidrug resistance-associated protein 2 (MRP2/ABCC2) haplotypes significantly affect the pharmacokinetics of tacrolimus in kidney transplant recipientsMutations in intracellular loops 1 and 3 lead to misfolding of human P-glycoprotein (ABCB1) that can be rescued by cyclosporine A, which reduces its association with chaperone Hsp70.
P2860
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P2860
Human P-glycoprotein transports cyclosporin A and FK506.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Human P-glycoprotein transports cyclosporin A and FK506.
@en
type
label
Human P-glycoprotein transports cyclosporin A and FK506.
@en
prefLabel
Human P-glycoprotein transports cyclosporin A and FK506.
@en
P2093
P1476
Human P-glycoprotein transports cyclosporin A and FK506.
@en
P2093
P304
P407
P577
1993-03-01T00:00:00Z