Long-term glycemic control with hepatic insulin gene therapy in streptozotocin-diabetic mice.

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An edible switch for gene therapy.Regenerative medicine and cell-based approaches to restore pancreatic function.

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Long-term glycemic control with hepatic insulin gene therapy in streptozotocin-diabetic mice.

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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name

Long-term glycemic control wit ...... streptozotocin-diabetic mice.

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Long-term glycemic control wit ...... streptozotocin-diabetic mice.

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Long-term glycemic control wit ...... streptozotocin-diabetic mice.

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Long-term glycemic control wit ...... streptozotocin-diabetic mice.

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Adam G Campbell

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Darin E Olson

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Dingwu Jia

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Miroslaw Kozlowski

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Peter M Thulé

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Sara Paveglio

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Shou You

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Yulin Lin

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P2860

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Self-complementary AAVs induce more potent transgene product-specific immune responses compared to a single-stranded genome

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype.

Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size.

Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins.

The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver.

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

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141-152

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scholarly article

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10.1002/JGM.2835

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8-9

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2015-07-20T00:00:00Z

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280219120

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26190010

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gene therapy

Long-term glycemic control with hepatic insulin gene therapy in streptozotocin-diabetic mice.

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P2860

Long-term glycemic control with hepatic insulin gene therapy in streptozotocin-diabetic mice.

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