NosA catalyzing carboxyl-terminal amide formation in nosiheptide maturation via an enamine dealkylation on the serine-extended precursor peptide.
about
Thiopeptide antibiotics: retrospective and recent advancesThioFinder: a web-based tool for the identification of thiopeptide gene clusters in DNA sequencesThiazole/oxazole-modified microcins: complex natural products from ribosomal templatesStructure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides BiosynthesisRevealing nature's synthetic potential through the study of ribosomal natural product biosynthesis.The posttranslational modification cascade to the thiopeptide berninamycin generates linear forms and altered macrocyclic scaffoldsCapture of micrococcin biosynthetic intermediates reveals C-terminal processing as an obligatory step for in vivo maturation.Biosynthesis of thiopeptide antibiotics and their pathway engineering.Muscarine, imidaozle, oxazole and thiazole alkaloids.Thiopeptide engineering: a multidisciplinary effort towards future drugs.YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function.Post-translational modifications involved in the biosynthesis of thiopeptide antibiotics.Crystallographic analysis of NosA, which catalyzes terminal amide formation in the biosynthesis of nosiheptide.Mutagenesis of NosM Leader Peptide Reveals Important Elements in Nosiheptide BiosynthesisThe C-terminal extended serine residue is absolutely required in nosiheptide maturation.Directly utilizing an endogenous gene to dissect regulatory elements in the biosynthetic gene cluster of nosiheptide.Effect analysis of mineral salt concentrations on nosiheptide production by Streptomyces actuosus Z-10 using response surface methodology.Enzymatic C-H Oxidation-Amidation Cascade in the Production of Natural and Unnatural Thiotetronate Antibiotics with Potentiated Bioactivity.Ribosomal Natural Products, Tailored To Fit.Rerouting the Pathway for the Biosynthesis of the Side Ring System of Nosiheptide: The Roles of NosI, NosJ, and NosK.Insight into bicyclic thiopeptide biosynthesis benefited from development of a uniform approach for molecular engineering and production improvement
P2860
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P2860
NosA catalyzing carboxyl-terminal amide formation in nosiheptide maturation via an enamine dealkylation on the serine-extended precursor peptide.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
NosA catalyzing carboxyl-termi ...... ne-extended precursor peptide.
@en
type
label
NosA catalyzing carboxyl-termi ...... ne-extended precursor peptide.
@en
prefLabel
NosA catalyzing carboxyl-termi ...... ne-extended precursor peptide.
@en
P2093
P2860
P356
P1476
NosA catalyzing carboxyl-termi ...... ne-extended precursor peptide.
@en
P2093
Rijing Liao
P2860
P304
16324-16326
P356
10.1021/JA106571G
P407
P50
P577
2010-11-03T00:00:00Z