about
Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis.NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.Salmonella-induced inflammasome activation in humans.Molecular determinants involved in activation of caspase 7Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.Quantifying Caspase-1 Activity in Murine Macrophages.Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion.Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular trapsThe Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responsesDimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasomeInterleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent SecretionGeneral in vitro caspase assay proceduresDivide to conquer: NLRP3 is activated on dispersed trans-Golgi networkMCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibitionVariation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonizationCaspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Dave Boucher
@ast
Dave Boucher
@en
Dave Boucher
@es
Dave Boucher
@nl
Dave Boucher
@sl
type
label
Dave Boucher
@ast
Dave Boucher
@en
Dave Boucher
@es
Dave Boucher
@nl
Dave Boucher
@sl
prefLabel
Dave Boucher
@ast
Dave Boucher
@en
Dave Boucher
@es
Dave Boucher
@nl
Dave Boucher
@sl
P1053
J-1830-2014
P106
P1153
57191099830
P21
P31
P3829
P496
0000-0003-0075-8893