HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models. - Wikidata - wikimedia - TriplyDB

HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models.

HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models.

http://www.wikidata.org/entity/Q41608936

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HDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases Synaptopathies: synaptic dysfunction in neurological disorders - A review from students to students A High Temperature-Dependent Mitochondrial Lipase EXTRA GLUME1 Promotes Floral Phenotypic Robustness against Temperature Fluctuation in Rice (Oryza sativa L.)HDAC1 links early life stress to schizophrenia-like phenotypes The development prospection of HDAC inhibitors as a potential therapeutic direction in Alzheimer's disease.HDAC inhibition promotes both initial consolidation and reconsolidation of spatial memory in mice.Satb2 determines miRNA expression and long-term memory in the adult central nervous system.Contribution of Neuroepigenetics to Huntington's Disease.Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia.Chromatin Changes Associated with Neuronal Maintenance and Their Pharmacological Application.Development of Allosteric Hydrazide-Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia.The epigenomics of schizophrenia, in the mouse.HDAC3 negatively regulates spatial memory in a mouse model of Alzheimer's disease.The BET/BRD inhibitor JQ1 improves brain plasticity in WT and APP mice.The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory.Epigenetics in Parkinson's Disease.A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer's Disease Mice.Systems approach to the pharmacological actions of HDAC inhibitors reveals EP300 activities and convergent mechanisms of regulation in diabetes.Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.Dietary Modulation of the Epigenome.[Epigenetic regulations and cerebral plasticity: towards new therapeutic options in neurodegenerative diseases?]Alzheimer's Disease and Histone Code Alterations.The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.Class I histone deacetylase (HDAC) inhibitor CI-994 promotes functional recovery following spinal cord injury.Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies

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HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models.

http://www.wikidata.org/entity/Q41608936

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

@zh-tw

2015年论文

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2015年论文

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2015年论文

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name

HDAC inhibitor-dependent trans ...... t in cognitive decline models.

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type

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HDAC inhibitor-dependent trans ...... t in cognitive decline models.

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HDAC inhibitor-dependent trans ...... t in cognitive decline models.

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Journal of Clinical Investigation

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HDAC inhibitor-dependent trans ...... nt in cognitive decline models

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P2093

André Fischer

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Anna-Lena Schütz

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Binu Ramachandran

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Camin Dean

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Gaurav Jain

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Hendrik Urbanke

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Jonas Barth

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Magdalena Navarro-Sala

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Reinhardt Lührmann

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Sankari Nagarajan

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P2860

Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease

The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing

HDAC2 negatively regulates memory formation and synaptic plasticity.

An epigenetic blockade of cognitive functions in the neurodegenerating brain

Exercise training increases size of hippocampus and improves memory

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.

Variation in alternative splicing across human tissues

Metabolomics of human brain aging and age-related neurodegenerative diseases

SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease

Chromatin modifications and their function

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3572-3584

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10.1172/JCI79942

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9

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125

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Steven A Johnsen

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2015-08-17T00:00:00Z

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26280576

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