Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules.
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Natural Proline-Rich Cyclopolypeptides from Marine Organisms: Chemistry, Synthetic Methodologies and Biological StatusThe insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycinMarine-derived anticancer agents in clinical trials.Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Impact of marine drugs on cytoskeleton-mediated reproductive eventsInteractions of antimitotic peptides and depsipeptides with tubulin.Drugs that target dynamic microtubules: a new molecular perspectiveAntivascular approaches to solid tumour therapy: evaluation of tubulin binding agentsStrategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates.Visualisation of a kinesin-13 motor on microtubule end mimics.Microtubule inhibitors as a potential treatment for malaria.Intracellular activation and deactivation of tasidotin, an analog of dolastatin 15: correlation with cytotoxicityADME of antibody-maytansinoid conjugatesBacterial symbionts in agricultural systems provide a strategic source for antibiotic discovery.Targeting castration-resistant prostate cancer with monoclonal antibodies and constructs.Natural Compounds as Modulators of Cell Cycle Arrest: Application for Anticancer Chemotherapies.Cytotoxicity, cell cycle kinetics and morphonuclear-induced effects of Vinca alkaloid anticancer agents.Anti-microtubule activity of tubeimoside I and its colchicine binding site of tubulin.(-)-Doliculide, a new macrocyclic depsipeptide enhancer of actin assembly.Microtermolides A and B from termite-associated Streptomyces sp. and structural revision of vinylamycin.Antimicrotubular and cytotoxic activity of geiparvarin analogues, alone and in combination with paclitaxel.Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel-Dreyer chromatography.Antitumor activity of TZT-1027, a novel dolastatin 10 derivative.Therapeutic Properties and Biological Benefits of Marine-Derived Anticancer Peptides.Characterization of the interaction of TZT-1027, a potent antitumor agent, with tubulin.Smenamide A Analogues. Synthesis and Biological Activity on Multiple Myeloma Cells.Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural Products
P2860
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P2860
Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Dolastatin 15, a potent antimi ...... ects of cellular microtubules.
@en
type
label
Dolastatin 15, a potent antimi ...... ects of cellular microtubules.
@en
prefLabel
Dolastatin 15, a potent antimi ...... ects of cellular microtubules.
@en
P2093
P1476
Dolastatin 15, a potent antimi ...... ects of cellular microtubules.
@en
P2093
P304
P356
10.1016/0006-2952(92)90153-A
P407
P577
1992-06-01T00:00:00Z