Assembly and transport properties of invariant chain trimers and HLA-DR-invariant chain complexes.
about
A functional heteromeric MIF receptor formed by CD74 and CXCR4Mapping functional regions in the lumenal domain of the class II-associated invariant chainHuman leukocyte Antigen-DM polymorphisms in autoimmune diseasesThe use of flow cytometry to assess a novel drug efficacy in multiple sclerosisThe invariant chain is required for intracellular transport and function of major histocompatibility complex class II moleculesDefective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expressionCathepsin S inhibitor prevents autoantigen presentation and autoimmunityA role for calnexin (IP90) in the assembly of class II MHC moleculesHuman immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinaseProteolysis of major histocompatibility complex class II-associated invariant chain is regulated by the alternatively spliced gene product, p41.Stoichiometry of HLA class II-invariant chain oligomersInteraction of MHC class II molecules with the invariant chain: role of the invariant chain (81-90) regionI-Ag7 is subject to post-translational chaperoning by CLIP.Expression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteinsTripping on acid: trans-kingdom perspectives on biological acids in immunity and pathogenesis.Molecular dynamics simulations to provide insights into epitopes coupled to the soluble and membrane-bound MHC-II complexes.Parasite Manipulation of the Invariant Chain and the Peptide Editor H2-DM Affects Major Histocompatibility Complex Class II Antigen Presentation during Toxoplasma gondii Infection.Efficient endosomal localization of major histocompatibility complex class II-invariant chain complexes requires multimerization of the invariant chain targeting sequence.Isoforms of the invariant chain regulate transport of MHC class II molecules to antigen processing compartmentsProtein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable componentsThe anti-CD74 humanized monoclonal antibody, milatuzumab, which targets the invariant chain of MHC II complexes, alters B-cell proliferation, migration, and adhesion molecule expression.Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles.HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR moleculesTransport and intracellular distribution of MHC class II molecules and associated invariant chain in normal and antigen-processing mutant cell lines.A novel regulatory pathway for autoimmune disease: binding of partial MHC class II constructs to monocytes reduces CD74 expression and induces both specific and bystander T-cell toleranceSalmonella polarises peptide-MHC-II presentation towards an unconventional Type B CD4+ T-cell responseCathepsin S activity regulates antigen presentation and immunity.Exposing the Specific Roles of the Invariant Chain Isoforms in Shaping the MHC Class II Peptidome.Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain.How MHC class II molecules reach the endocytic pathway.MHC class II antigen presentation by dendritic cells regulated through endosomal sorting.Structural Insights Into HLA-DM Mediated MHC II Peptide Exchange.Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules.Shark class II invariant chain reveals ancient conserved relationships with cathepsins and MHC class II.Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.Introducing endogenous antigens into the major histocompatibility complex (MHC) class II presentation pathway. Both Ii mediated inhibition and enhancement of endogenous peptide/MHC class II presentation require the same Ii domains.HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway.
P2860
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P2860
Assembly and transport properties of invariant chain trimers and HLA-DR-invariant chain complexes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Assembly and transport propert ...... -DR-invariant chain complexes.
@en
type
label
Assembly and transport propert ...... -DR-invariant chain complexes.
@en
prefLabel
Assembly and transport propert ...... -DR-invariant chain complexes.
@en
P1476
Assembly and transport propert ...... -DR-invariant chain complexes.
@en
P2093
P304
P407
P577
1992-06-01T00:00:00Z