Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts--correlation with prostaglandin upregulation.
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The amazing osteocyteBiology of Bone Tissue: Structure, Function, and Factors That Influence Bone CellsIn vitro and in vivo approaches to study osteocyte biologyOsteocytes: master orchestrators of boneIn Vitro Bone Cell Models: Impact of Fluid Shear Stress on Bone FormationIn silico bone mechanobiology: modeling a multifaceted biological systemPhysiological mechanisms and therapeutic potential of bone mechanosensing.Cyclic tensile strain suppresses catabolic effects of interleukin-1beta in fibrochondrocytes from the temporomandibular jointFocal adhesion kinase plays a role in osteoblast mechanotransduction in vitro but does not affect load-induced bone formation in vivoOrthodontic force stimulates eNOS and iNOS in rat osteocytesMechanotransduction as an Adaptation to Gravity.Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway.In situ intracellular calcium oscillations in osteocytes in intact mouse long bones under dynamic mechanical loading.Different responsiveness of cells from adult and neonatal mouse bone to mechanical and biochemical challenge.Estrogen enhances mechanical stress-induced prostaglandin production by bone cells from elderly women.Increased nitric oxide-mediated vasodilation of bone resistance arteries is associated with increased trabecular bone volume after endurance training in rats.Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways.Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells.Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes.Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in boneSkeletal adaptation to intramedullary pressure-induced interstitial fluid flow is enhanced in mice subjected to targeted osteocyte ablation.Responses of bone cells to biomechanical forces in vitro.Modulation of membrane traffic by mechanical stimuli.Low-magnitude mechanical loading becomes osteogenic when rest is inserted between each load cycle.Biomechanical forces in the skeleton and their relevance to bone metastasis: biology and engineering considerations.Stepwise increasing and decreasing fluid shear stresses differentially regulate the functions of osteoblastsAdipose-derived stem cells in functional bone tissue engineering: lessons from bone mechanobiology.Osteocyte shape and mechanical loading.How do tissues respond and adapt to stresses around a prosthesis? A primer on finite element stress analysis for orthopaedic surgeons.TIEG1-NULL OSTEOCYTES DISPLAY DEFECTS IN THEIR MORPHOLOGY, DENSITY AND SURROUNDING BONE MATRIX.Loss of trabeculae by mechano-biological means may explain rapid bone loss in osteoporosis.In vivo mechanical loading rapidly activates β-catenin signaling in osteocytes through a prostaglandin mediated mechanism.Blood and interstitial flow in the hierarchical pore space architecture of bone tissue"Culture shock" from the bone cell's perspective: emulating physiological conditions for mechanobiological investigations.Connexin43 and pannexin1 channels in osteoblasts: who is the "hemichannel"?Gap junctions and hemichannels in signal transmission, function and development of boneMitogen-activated Protein Kinase (MAPK) Activated by Prostaglandin E2 Phosphorylates Connexin 43 and Closes Osteocytic Hemichannels in Response to Continuous Flow Shear Stress.Cellular fluid shear stress on implant surfaces-establishment of a novel experimental set upEffects of growth factors and cytokines on osteoblast differentiation.For whom the bell tolls: distress signals from long-lived osteocytes and the pathogenesis of metabolic bone diseases.
P2860
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P2860
Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts--correlation with prostaglandin upregulation.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Pulsating fluid flow increases ...... th prostaglandin upregulation.
@en
type
label
Pulsating fluid flow increases ...... th prostaglandin upregulation.
@en
prefLabel
Pulsating fluid flow increases ...... th prostaglandin upregulation.
@en
P2093
P356
P1476
Pulsating fluid flow increases ...... th prostaglandin upregulation.
@en
P2093
Klein-Nulend J
Nijweide PJ
Semeins CM
P304
P356
10.1006/BBRC.1995.2822
P577
1995-12-01T00:00:00Z