The amino-terminal portion of CFTR forms a regulated Cl- channel.
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The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesisChloride channels: an emerging molecular pictureDevelopment of CFTR StructureDeletion of CFTR translation start site reveals functional isoforms of the protein in CF patients.The role of the UPS in cystic fibrosis.ADP inhibits function of the ABC transporter cystic fibrosis transmembrane conductance regulator via its adenylate kinase activity.Cystic fibrosis transmembrane conductance regulator and the outwardly rectifying chloride channel: a relationship between two chloride channels expressed in epithelial cells.Conformation, independent of charge, in the R domain affects cystic fibrosis transmembrane conductance regulator channel openingsMutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function inCharacteristics of peptide and major histocompatibility complex class I/beta 2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2)Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH(2)-terminal nucleotide binding domain.Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domainsMutations at arginine 352 alter the pore architecture of CFTR.Inhibition of SMG-8, a subunit of SMG-1 kinase, ameliorates nonsense-mediated mRNA decay-exacerbated mutant phenotypes without cytotoxicity.Acute inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel by thyroid hormones involves multiple mechanisms.Structural cues involved in endoplasmic reticulum degradation of G85E and G91R mutant cystic fibrosis transmembrane conductance regulator.Mechanism of dysfunction of two nucleotide binding domain mutations in cystic fibrosis transmembrane conductance regulator that are associated with pancreatic sufficiency.Adverse effects of low level heavy metal exposure on male reproductive function.The first nucleotide binding fold of the cystic fibrosis transmembrane conductance regulator can function as an active ATPase.Identification of the cystic fibrosis transmembrane conductance regulator domains that are important for interactions with ROMK2.The second half of the cystic fibrosis transmembrane conductance regulator forms a functional chloride channel.Truncation of MalF results in lactose transport via the maltose transport system of Escherichia coli.Invasion of human epithelial cells by Pseudomonas aeruginosa involves src-like tyrosine kinases p60Src and p59Fyn.A plethora of cardiac chloride conductances: molecular diversity or a related gene family.The two halves of CFTR form a dual-pore ion channel.New pharmaceutical approaches to the treatment of cystic fibrosis.Functional dissection of the R domain of cystic fibrosis transmembrane conductance regulator.Regulation of Cl-/ HCO3- exchange by cystic fibrosis transmembrane conductance regulator expressed in NIH 3T3 and HEK 293 cells.Function of the R domain in the cystic fibrosis transmembrane conductance regulator chloride channel.Protein structures in receptor classification.Interaction between cystic fibrosis transmembrane conductance regulator and outwardly rectified chloride channels.Cystic fibrosis transmembrane conductance regulator. Permeant ions find the pore.Stable dimeric assembly of the second membrane-spanning domain of CFTR (cystic fibrosis transmembrane conductance regulator) reconstitutes a chloride-selective pore.Reconstitution of ATP-dependent leukotriene C4 transport by Co-expression of both half-molecules of human multidrug resistance protein in insect cells.Determination of the functional unit of the cystic fibrosis transmembrane conductance regulator chloride channel. One polypeptide forms one pore.Mercury and zinc differentially inhibit shark and human CFTR orthologues: involvement of shark cysteine 102.Rescue of functional DeltaF508-CFTR channels by co-expression with truncated CFTR constructs in COS-1 cells.Nonsense-mediated decay: linking a basic cellular process to human disease.Function of Xenopus cystic fibrosis transmembrane conductance regulator (CFTR) Cl channels and use of human-Xenopus chimeras to investigate the pore properties of CFTR.Aquaporin 3 cloned from Xenopus laevis is regulated by the cystic fibrosis transmembrane conductance regulator.
P2860
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P2860
The amino-terminal portion of CFTR forms a regulated Cl- channel.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The amino-terminal portion of CFTR forms a regulated Cl- channel.
@en
type
label
The amino-terminal portion of CFTR forms a regulated Cl- channel.
@en
prefLabel
The amino-terminal portion of CFTR forms a regulated Cl- channel.
@en
P2093
P1433
P1476
The amino-terminal portion of CFTR forms a regulated Cl- channel
@en
P2093
P304
P356
10.1016/0092-8674(94)90385-9
P407
P577
1994-03-01T00:00:00Z