about
Alteration of protein function by a silent polymorphism linked to tRNA abundance.A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia.Gel-forming mucins form distinct morphologic structures in airwaysCystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth.A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator.Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice.Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epitheliaThe ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs.Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass.Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function inBovine AAV transcytosis inhibition by tannic acid results in functional expression of CFTR in vitro and altered biodistribution in vivo.Processing and function of CFTR-DeltaF508 are species-dependent.Pancreatic and biliary secretion are both altered in cystic fibrosis pigs.Acidic pH increases airway surface liquid viscosity in cystic fibrosisCystic Fibrosis Transmembrane Conductance Regulator in Sarcoplasmic Reticulum of Airway Smooth Muscle. Implications for Airway ContractilityThe porcine lung as a potential model for cystic fibrosisAirway acidification initiates host defense abnormalities in cystic fibrosis mice.Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.Relationships among CFTR expression, HCO3- secretion, and host defense may inform gene- and cell-based cystic fibrosis therapiesDisruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.Understanding how cystic fibrosis mutations cause a loss of Cl- channel function.Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties.The amino-terminal portion of CFTR forms a regulated Cl- channel.Expression and characterization of the cystic fibrosis transmembrane conductance regulator.Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis.Curcumin stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity.Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling.Structural biology. The ABC of a versatile engine.Effect of cystic fibrosis-associated mutations in the fourth intracellular loop of cystic fibrosis transmembrane conductance regulator.Erythrocyte incorporation of ingested 58-iron by infantsCystic fibrosis transmembrane conductance regulator Cl- channels with R domain deletions and translocations show phosphorylation-dependent and -independent activityAssociation of domains within the cystic fibrosis transmembrane conductance regulatorCystic fibrosis problem probed by proteolysis
P50
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P50
description
Forscher
@de
chercheur
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investigador
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onderzoeker
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researcher
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հետազոտող
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研究者
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name
Lynda S Ostedgaard
@ast
Lynda S Ostedgaard
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Lynda S Ostedgaard
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Lynda S Ostedgaard
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type
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Lynda S Ostedgaard
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Lynda S Ostedgaard
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Lynda S Ostedgaard
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Lynda S Ostedgaard
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prefLabel
Lynda S Ostedgaard
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Lynda S Ostedgaard
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Lynda S Ostedgaard
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Lynda S Ostedgaard
@nl
P106
P1153
6701764343
P31
P496
0000-0001-7717-3442