Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.
about
Investigation of allosteric modulation mechanism of metabotropic glutamate receptor 1 by molecular dynamics simulations, free energy and weak interaction analysisA G Protein-Coupled Receptor Dimerization Interface in Human Cone OpsinsStructural mechanism of ligand activation in human calcium-sensing receptor.Apelin receptor homodimer-oligomers revealed by single-molecule imaging and novel G protein-dependent signaling.Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophreniaPhospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR.Conformational dynamics of a class C G-protein-coupled receptorDynamic Cholesterol-Conditioned Dimerization of the G Protein Coupled Chemokine Receptor Type 4.Impact of Lipid Composition and Receptor Conformation on the Spatio-temporal Organization of μ-Opioid Receptors in a Multi-component Plasma Membrane Model.Peptide-guided targeting of GPR55 for anti-cancer therapy.Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction InterfaceSystematic substitutions at BLIP position 50 result in changes in binding specificity for class A β-lactamases.New paradigms in GPCR drug discovery.Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.Revealing G-protein-coupled receptor oligomerization at the single-molecule level through a nanoscopic lens: methods, dynamics and biological function.Signaling within Allosteric Machines: Signal Transmission Pathways Inside G Protein-Coupled Receptors.Organization and functions of mGlu and GABAB receptor complexes.Structural insight to mutation effects uncover a common allosteric site in class C GPCRsThe anatomy of mammalian sweet taste receptors.Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand.Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling.Activation mechanism of the G protein-coupled sweet receptor heterodimer with sweeteners and allosteric agonists.Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors.Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer.Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ-46281222.Opioid receptors mediate inotropic and depressor effects of apelin in rats with 2K1C-induced chronic renovascular hypertension.Class C G protein-coupled receptors: reviving old couples with new partners.Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.The Class-A GPCR Dopamine D2 Receptor Forms Transient Dimers Stabilized by Agonists: Detection by Single-Molecule Tracking.Structural biology of GABAB receptor.HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.Downregulation of a GPCR by β-Arrestin2-Mediated Switch from an Endosomal to a TGN Recycling Pathway.Dual-color reporter switching system to discern dimer formations of G-protein-coupled receptors using Cre/loxP site-specific recombination in yeast.Molecular dynamics simulations and structure-based network analysis reveal structural and functional aspects of G-protein coupled receptor dimer interactions.Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs.Dynamic tuneable G protein-coupled receptor monomer-dimer populations.Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics.Integrated Structural Biology for α-Helical Membrane Protein Structure DeterminationEvidence of Alternative Splicing as a Regulatory Mechanism for Kissr2 in Pejerrey Fish
P2860
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P2860
Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.
@en
type
label
Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.
@en
prefLabel
Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.
@en
P2093
P2860
P50
P356
P1476
Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer
@en
P2093
Jianfeng Liu
Pauline Scholler
P2860
P2888
P304
P356
10.1038/NCHEMBIO.1711
P577
2014-12-15T00:00:00Z