Human damage-specific DNA-binding protein p48. Characterization of XPE mutations and regulation following UV irradiation.
about
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivoUV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradationStructural basis of UV DNA-damage recognition by the DDB1-DDB2 complexSequential binding of UV DNA damage binding factor and degradation of the p48 subunit as early events after UV irradiation.Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex.Circadian clock control of the cellular response to DNA damageHepatitis B virus X protein and simian virus 5 V protein exhibit similar UV-DDB1 binding properties to mediate distinct activitiesGlobal-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo ModifiersXeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulationStructure and Stability of Duplex DNA Containing (5′ S )-5′,8-Cyclo-2′-deoxyadenosine: An Oxidatively Generated Lesion Repaired by NERNuclear transport of human DDB protein induced by ultraviolet lightHepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repairRegulation and role of Arabidopsis CUL4-DDB1A-DDB2 in maintaining genome integrity upon UV stressTumor-prone phenotype of the DDB2-deficient miceTwo-stage dynamic DNA quality check by xeroderma pigmentosum group C protein.Damaged DNA-binding protein DDB stimulates the excision of cyclobutane pyrimidine dimers in vitro in concert with XPA and replication protein A.DNA damage in the nucleosome core is refractory to repair by human excision nuclease.DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair.Xeroderma pigmentosum complementation group E protein (XPE/DDB2): purification of various complexes of XPE and analyses of their damaged DNA binding and putative DNA repair properties.Damaged DNA binding protein 2 plays a role in breast cancer cell growthChromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity.RETRACTED: DDB2, an essential mediator of premature senescenceSimilar nucleotide excision repair capacity in melanocytes and melanoma cellsIdentification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells.The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells.Restoration of UV sensitivity in UV-resistant HeLa cells by antisense-mediated depletion of damaged DNA-binding protein 2 (DDB2).Strand- and site-specific DNA lesion demarcation by the xeroderma pigmentosum group D helicase.NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sitesCullins and cancer.Drosophila damage-specific DNA-binding protein 1 (D-DDB1) is controlled by the DRE/DREF system.DDB1-DDB2 (xeroderma pigmentosum group E) protein complex recognizes a cyclobutane pyrimidine dimer, mismatches, apurinic/apyrimidinic sites, and compound lesions in DNA.The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability.Drosophila damaged DNA-binding protein 1 is an essential factor for development.Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein.p21 cooperates with DDB2 protein in suppression of ultraviolet ray-induced skin malignancies.DDB2 promotes chromatin decondensation at UV-induced DNA damage.Pathogenic Role of the CRL4 Ubiquitin Ligase in Human DiseaseMultiple skin cancers in adults with mutations in the XP-E (DDB2) DNA repair gene.DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen.
P2860
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P2860
Human damage-specific DNA-binding protein p48. Characterization of XPE mutations and regulation following UV irradiation.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Human damage-specific DNA-bind ...... tion following UV irradiation.
@en
type
label
Human damage-specific DNA-bind ...... tion following UV irradiation.
@en
prefLabel
Human damage-specific DNA-bind ...... tion following UV irradiation.
@en
P2093
P2860
P356
P1476
Human damage-specific DNA-bind ...... ation following UV irradiation
@en
P2093
P2860
P304
21422-21428
P356
10.1074/JBC.M000960200
P407
P577
2000-07-01T00:00:00Z