Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein
about
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivoUV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradationDDB, a putative DNA repair protein, can function as a transcriptional partner of E2F1.Mutations specific to the xeroderma pigmentosum group E Ddb- phenotypeSequential binding of UV DNA damage binding factor and degradation of the p48 subunit as early events after UV irradiation.UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylationHepatitis B virus X protein interacts with a probable cellular DNA repair proteinNuclear transport of human DDB protein induced by ultraviolet lightNucleotide excision repair proteins rapidly accumulate but fail to persist in human XP-E (DDB2 mutant) cellsCharacterization of DNA recognition by the human UV-damaged DNA-binding proteinRelationship of the xeroderma pigmentosum group E DNA repair defect to the chromatin and DNA binding proteins UV-DDB and replication protein A.Xeroderma pigmentosum complementation group E protein (XPE/DDB2): purification of various complexes of XPE and analyses of their damaged DNA binding and putative DNA repair properties.DDB1 maintains genome integrity through regulation of Cdt1DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.Hepatitis B virus X protein interferes with cellular DNA repair.Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways.The naturally occurring mutants of DDB are impaired in stimulating nuclear import of the p125 subunit and E2F1-activated transcription.The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells.Restoration of UV sensitivity in UV-resistant HeLa cells by antisense-mediated depletion of damaged DNA-binding protein 2 (DDB2).Drosophila damage-specific DNA-binding protein 1 (D-DDB1) is controlled by the DRE/DREF system.repE--the Dictyostelium homolog of the human xeroderma pigmentosum group E gene is developmentally regulated and contains a leucine zipper motifRapid changes of nucleotide excision repair gene expression following UV-irradiation and cisplatin treatment of Dictyostelium discoideum.Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repairXeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein.Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repairMultiple skin cancers in adults with mutations in the XP-E (DDB2) DNA repair gene.Damaged DNA binding protein 2 in reactive oxygen species (ROS) regulation and premature senescenceFunctional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro systemEvidence for a novel DNA damage binding protein in human cells.DNA damage response.A novel role for DNA photolyase: binding to DNA damaged by drugs is associated with enhanced cytotoxicity in Saccharomyces cerevisiaeCharacterization of a Schizosaccharomyces pombe strain deleted for a sequence homologue of the human damaged DNA binding 1 (DDB1) gene.Electrophoretic mobility shift assays for protein-DNA complexes involved in DNA repair.p48 Activates a UV-damaged-DNA binding factor and is defective in xeroderma pigmentosum group E cells that lack binding activityPSI-BLAST searches using hidden markov models of structural repeats: prediction of an unusual sliding DNA clamp and of beta-propellers in UV-damaged DNA-binding protein.DDB2 induces nuclear accumulation of the hepatitis B virus X protein independently of binding to DDB1.Basal transcriptional regulation of human damage-specific DNA-binding protein genes DDB1 and DDB2 by Sp1, E2F, N-myc and NF1 elements.The xeroderma pigmentosum group E gene product DDB2 activates nucleotide excision repair by regulating the level of p21Waf1/Cip1.Human damage-specific DNA-binding protein p48. Characterization of XPE mutations and regulation following UV irradiation.The nucleotide excision repair protein XPC is essential for bulky DNA adducts to promote interleukin-6 expression via the activation of p38-SAPK.
P2860
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P2860
Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein
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1994 nî lūn-bûn
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1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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1994 թվականի ապրիլին հրատարակված գիտական հոդված
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1994年の論文
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年學術文章
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Correction of the DNA repair d ...... f a DNA damage-binding protein
@ast
Correction of the DNA repair d ...... f a DNA damage-binding protein
@en
Correction of the DNA repair d ...... f a DNA damage-binding protein
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label
Correction of the DNA repair d ...... f a DNA damage-binding protein
@ast
Correction of the DNA repair d ...... f a DNA damage-binding protein
@en
Correction of the DNA repair d ...... f a DNA damage-binding protein
@nl
prefLabel
Correction of the DNA repair d ...... f a DNA damage-binding protein
@ast
Correction of the DNA repair d ...... f a DNA damage-binding protein
@en
Correction of the DNA repair d ...... f a DNA damage-binding protein
@nl
P2093
P2860
P356
P1476
Correction of the DNA repair d ...... f a DNA damage-binding protein
@en
P2093
J H Hoeijmakers
W Vermeulen
P2860
P304
P356
10.1073/PNAS.91.9.4053
P407
P577
1994-04-26T00:00:00Z