Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts.
about
Protein kinase C delta blocks immediate-early gene expression in senescent cells by inactivating serum response factorA biomarker that identifies senescent human cells in culture and in aging skin in vivomiR-17-92 cluster: ups and downs in cancer and agingInduction of senescence-like phenotypes by forced expression of hic-5, which encodes a novel LIM motif protein, in immortalized human fibroblastsOxygen sensitivity severely limits the replicative lifespan of murine fibroblastsAging and cancer: issues of basic and clinical science.Development of a human mitochondrial oligonucleotide microarray (h-MitoArray) and gene expression analysis of fibroblast cell lines from 13 patients with isolated F1Fo ATP synthase deficiency.A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen.One systemic administration of transforming growth factor-beta 1 reverses age- or glucocorticoid-impaired wound healingSenescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.Genetic and molecular analysis of a long-lived strain of Podospora anserina.Increased activity of p53 in senescing fibroblasts.Anti-aging data and support claims--consensus statement.p38 MAP kinase-dependent regulation of the expression level and subcellular distribution of heterogeneous nuclear ribonucleoprotein A1 and its involvement in cellular senescence in normal human fibroblasts.Creation of psoriatic plaques: the ultimate tumor suppressor pathway. A new model for an ancient T-cell-mediated skin disease. Viewpoint.Growth-related gene expression in type 2 alveolar epithelial cells.Elevation of cell cycle control proteins during spontaneous immortalization of human keratinocytes.Terminal differentiation and senescence in the human melanocyte: repression of tyrosine-phosphorylation of the extracellular signal-regulated kinase 2 selectively defines the two phenotypes.Net expression inhibits the growth of pancreatic ductal adenocarcinoma cell PL45 in vitro and in vivoThe ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway.Suppression of calcium-dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein.Molecular mechanisms and in vivo mouse models of skin aging associated with dermal matrix alterations.Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.Adipocyte differentiation selectively represses the serum inducibility of c-jun and junB by reversible transcription-dependent mechanisms.Ageing and photoageing of the skin: observations at the cellular and molecular level.The cultured diploid fibroblast as a model for the study of cellular aging.Cellular senescence.Senescence of immortal human fibroblasts by the introduction of normal human chromosome 6Age-related differences in the expression of proto-oncogene and contractile protein genes in response to pressure overload in the rat myocardium.Gene expression in quiescent and senescent fibroblasts.Cellular senescence and organismal aging.Oxidative stress in aging human skin.Immortalized cells as experimental models to study cancer.Twenty years of progress in biogerontology research.Expression of c-fos and AP-1 activity in senescent human fibroblasts is not sufficient for DNA synthesisInhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein.Rat embryo fibroblasts immortalized with simian virus 40 large T antigen undergo senescence upon its inactivationHuman fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent.Loss of serum response element-binding activity and hyperphosphorylation of serum response factor during cellular aging.Extended life span of human endometrial stromal cells transfected with cloned origin-defective, temperature-sensitive simian virus 40.
P2860
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P2860
Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Repression of c-fos transcript ...... n senescent human fibroblasts.
@en
type
label
Repression of c-fos transcript ...... n senescent human fibroblasts.
@en
prefLabel
Repression of c-fos transcript ...... n senescent human fibroblasts.
@en
P356
P1433
P1476
Repression of c-fos transcript ...... n senescent human fibroblasts.
@en
P2093
P304
P356
10.1126/SCIENCE.2104680
P407
P577
1990-01-01T00:00:00Z